Gliomas are the most aggressive and lethal tumors of the central nervous system, for which
few therapeutic options exist. Surgical resection is the primary treatment for most gliomas; …

Cancers of the brain remain one of the greatest medical challenges. Traditional surgery and
chemo-radiation therapy are unable to eradicate diffuse cancer cells and tumor recurrence …

Therapeutically engineered stem cells have shown promise for glioblastoma multiforme
(GBM) therapy; however, key preclinical studies are urgently needed for their clinical …

OBJECTIVE High-grade glial brain tumors are often characterized by an elevated
expression of the tumorigenic epidermal growth factor receptor variant III (EGFRvIII). The …

Purpose To explore the role of dynamic contrast material–enhanced magnetic resonance
(MR) imaging in the differentiation of true progression from pseudoprogression in patients …

The substrates and mechanisms of ubiquitin specific peptidase 7 (USP7) in glioma remain
unclear. Lysine‑specific demethylase 1 (LSD1) may undergo proteasomal degradation; …

Objective The purpose of this study was to differentiate true progression from
pseudoprogression of glioblastomas treated with concurrent chemoradiotherapy (CCRT) …

In the present study, the PCL-Diol-b-PU/Au nanocompsite nanofibers were fabricated via
electrospinning process during two different stages to load an anticancer temozolomide …

Engineered stem cell (SC)-based therapy holds enormous promise for treating the incurable
brain cancer glioblastoma (GBM). Retaining the cytotoxic SCs in the surgical cavity after …

Purpose: Glioblastoma is the most common adult primary malignant intracranial cancer. It is
associated with poor outcomes because of its invasiveness and resistance to multimodal …