Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications

BR England, GM Thiele, DR Anderson, TR Mikuls - Bmj, 2018 - bmj.com
Rheumatoid arthritis is a systemic autoimmune disease characterized by excess morbidity
and mortality from cardiovascular disease. Mechanisms linking rheumatoid arthritis and …

Autoimmune atherosclerosis in 3D: How it develops, how to diagnose and what to do

Z Szekanecz, G Kerekes, E Végh, Z Kardos… - Autoimmunity …, 2016 - Elsevier
Autoimmune-inflammatory rheumatic diseases, such as rheumatoid arthritis (RA) have been
associated with autoimmune atherosclerosis leading to increased cardiovascular risk …

Cardiovascular risk in rheumatoid arthritis and mechanistic links: from pathophysiology to treatment

GE Fragoulis, I Panayotidis… - Current Vascular …, 2020 - ingentaconnect.com
Rheumatoid arthritis (RA) is an autoimmune inflammatory arthritis. Inflammation, however,
can spread beyond the joints to involve other organs. During the past few years, it has been …

[PDF][PDF] Phenome‐wide association study of autoantibodies to citrullinated and noncitrullinated epitopes in rheumatoid arthritis

KP Liao, JA Sparks, BP Hejblum, IH Kuo… - Arthritis & …, 2017 - Wiley Online Library
Objective Patients with rheumatoid arthritis (RA) develop autoantibodies against a spectrum
of antigens, but the clinical significance of these autoantibodies is unclear. Using a …

Association of anti–citrullinated peptide antibodies with coronary artery calcification in rheumatoid arthritis

L Geraldino‐Pardilla, JT Giles, J Sokolove… - Arthritis care & …, 2017 - Wiley Online Library
Objective Citrullinated proteins have been found within atherosclerotic plaque. However,
studies evaluating the association between anti–citrullinated protein antibodies (ACPAs) …

Anti-carbamylated protein autoantibodies associated with mortality in Spanish rheumatoid arthritis patients

L Vidal-Bralo, E Perez-Pampin, C Regueiro, A Montes… - PLoS …, 2017 - journals.plos.org
Patients with rheumatoid arthritis (RA) have an increased mortality rate that is associated
with the presence of RA-specific autoantibodies in many studies. However, the relative role …

Immunotherapy for the rheumatoid arthritis-associated coronary artery disease: promise and future

L Wang, Y Zhang, SY Zhang - Chinese Medical Journal, 2019 - mednexus.org
Objective: To review the latest progress on the pathogenic mechanism and management of
rheumatoid arthritis (RA)-associated coronary artery disease (CAD), and propose advice on …

Long-term mortality in patients with ST-segment elevation myocardial infarction is associated with anti-citrullinated protein antibodies

MPJ Hermans, D van der Velden, JMM Cabezas… - International Journal of …, 2017 - Elsevier
Background Cardiovascular (CV) mortality is higher in patients with rheumatoid arthritis
(RA), in particular when anti-citrullinated protein antibodies (ACPA) are present. Recently …

Association between biologic disease modifying anti-rheumatic drugs and incident hypertension in patients with rheumatoid arthritis: results from prospective …

SK Kim, SG Kwak, JY Choe - Medicine, 2020 - journals.lww.com
There has been some debate between biologic disease modifying anti-rheumatic drugs
(bDMARDs) treatment and hypertension (HTN) in rheumatoid arthritis (RA). The aim of this …

Citrullinated and carbamylated proteins in extracellular microvesicles from plasma of patients with rheumatoid arthritis

FM Ucci, S Recalchi, C Barbati, V Manganelli… - …, 2023 - academic.oup.com
Objectives To investigate the expression of citrullinated and carbamylated proteins in
extracellular microvesicles (EMVs) from RA patients. Methods We enrolled 24 RA naïve for …