Due to lack of specification and solubility of drug molecules, patients have to take high
doses of the drug to achieve the desired therapeutic effects for the treatment of diseases. To …

The oral pathway is considered as the most common method for drug administration,
although many drugs, especially the highly pH-and/or enzymatic biodegradable peptide …

The efficient and safe delivery of therapeutic drugs, proteins, and nucleic acids are essential
for meaningful therapeutic benefits. The field of nanomedicine shows promising implications …

One of the greatest challenges in the field of medicine is the effective and efficient drug
delivery to the defected cells or tumor cells with minimal toxic side effects. Due to lacking …

Abstract Recently, nano-silica (NS) particles with their tailorable property had gained
widespread attention due to their broad and emerging application areas, which included …

Growing interest in lanthanide-doped nanoparticles for biological and medical uses has
brought particular attention to their safety concerns. However, the intrinsic toxicity of this new …

We developed a potential pH-responsive protein drug delivery system based on aldehyde-
functionalized dendritic mesoporous silica nanoparticles (DMSNs-CHO) as nanocarriers …

Advances in nanotechnology for drug delivery are fostering significant progress in medicine
and diagnostics. The multidisciplinary nature of the nanotechnology field encouraged the …

A novel procedure for the synthesis of polyethylenimine (PEI)–silica nanocomposite
particles with high adsorption capacities has been developed based on an emulsion …

Silica nanoparticles appear as promising drug carriers for intracellular delivery. However,
the mechanisms by which they are degraded within cells remain largely unknown. In this …