Spatial navigation deficits—overlooked cognitive marker for preclinical Alzheimer disease?

G Coughlan, J Laczó, J Hort, AM Minihane… - Nature Reviews …, 2018 - nature.com
Detection of incipient Alzheimer disease (AD) pathophysiology is critical to identify
preclinical individuals and target potentially disease-modifying therapies towards them …

What determines our navigational abilities?

T Wolbers, M Hegarty - Trends in cognitive sciences, 2010 - cell.com
The ability to find one's way in our complex environments represents one of the most
fundamental cognitive functions. Although involving basic perceptual and memory related …

Spatial navigation in normal aging and the prodromal stage of Alzheimer's disease: insights from imaging and behavioral studies

S Lithfous, A Dufour, O Després - Ageing research reviews, 2013 - Elsevier
Normal aging and mild Alzheimer's disease (AD) are associated with declines in
navigational skills, including allocentric and egocentric representations, cognitive mapping …

How do (some) people make a cognitive map? Routes, places, and working memory.

SM Weisberg, NS Newcombe - Journal of Experimental Psychology …, 2016 - psycnet.apa.org
Research on the existence of cognitive maps and on the cognitive processes that support
effective navigation has often focused on functioning across individuals. However, there are …

Challenges for identifying the neural mechanisms that support spatial navigation: the impact of spatial scale

T Wolbers, JM Wiener - Frontiers in human neuroscience, 2014 - frontiersin.org
Spatial navigation is a fascinating behavior that is essential for our everyday lives. It involves
nearly all sensory systems, it requires numerous parallel computations, and it engages …

The hippocampus is required for short‐term topographical memory in humans

T Hartley, CM Bird, D Chan, L Cipolotti… - …, 2007 - Wiley Online Library
The hippocampus plays a crucial role within the neural systems for long‐term memory, but
little if any role in the short‐term retention of some types of stimuli. Nonetheless, the …

A controlled clinical comparison of attention performance in children with ADHD in a virtual reality classroom compared to standard neuropsychological methods

TD Parsons, T Bowerly, JG Buckwalter… - Child …, 2007 - Taylor & Francis
In this initial pilot study, a controlled clinical comparison was made of attention perforance in
children with attention deficit-hyperactivity disorder (ADHD) in a virtual reality (VR) …

Neuropsychology of environmental navigation in humans: review and meta-analysis of FMRI studies in healthy participants

M Boccia, F Nemmi, C Guariglia - Neuropsychology review, 2014 - Springer
In the past 20 years, many studies in the cognitive neurosciences have analyzed human
ability to navigate in recently learned and familiar environments by investigating the …

Cholinergic modulation of spatial learning, memory and navigation

N Solari, B Hangya - European Journal of Neuroscience, 2018 - Wiley Online Library
Spatial learning, including encoding and retrieval of spatial memories as well as holding
spatial information in working memory generally serving navigation under a broad range of …

Dissociable retrosplenial and hippocampal contributions to successful formation of survey representations

T Wolbers, C Büchel - Journal of Neuroscience, 2005 - Soc Neuroscience
During everyday navigation, humans encounter complex environments predominantly from
a first-person perspective. Behavioral evidence suggests that these perceptual experiences …