Brief update on endocytosis of nanomedicines
The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …
[HTML][HTML] Derangement of the endothelial glycocalyx in sepsis
The vascular endothelial surface is coated by the glycocalyx, a ubiquitous gel‐like layer
composed of a membrane‐binding domain that contains proteoglycans, glycosaminoglycan …
composed of a membrane‐binding domain that contains proteoglycans, glycosaminoglycan …
[HTML][HTML] Endothelial glycocalyx impairment in disease: focus on hyaluronan shedding
S Dogné, B Flamion - The American journal of pathology, 2020 - Elsevier
Hyaluronan (HA) is a ubiquitous glycosaminoglycan of the extracellular matrix. It is present
in the endothelial glycocalyx covering the apical surface of endothelial cells. The endothelial …
in the endothelial glycocalyx covering the apical surface of endothelial cells. The endothelial …
The glycocalyx and its role in vascular physiology and vascular related diseases
Purpose In 2007 the two senior authors wrote a review on the structure and function of the
endothelial glycocalyx layer (Weinbaum in Annu Rev Biomed Eng 9: 121–167, 2007). Since …
endothelial glycocalyx layer (Weinbaum in Annu Rev Biomed Eng 9: 121–167, 2007). Since …
Form follows function: the endothelial glycocalyx
A Suzuki, H Tomita, H Okada - Translational Research, 2022 - Elsevier
Three types of capillaries, namely continuous, fenestrated, and sinusoidal, form the
microvascular system; each type has a specialized structure and function to respond to the …
microvascular system; each type has a specialized structure and function to respond to the …
Endothelial damage in septic shock patients as evidenced by circulating syndecan-1, sphingosine-1-phosphate and soluble VE-cadherin: a substudy of ALBIOS
A Piotti, D Novelli, JMTA Meessen, D Ferlicca… - Critical Care, 2021 - Springer
Background Septic shock is characterized by breakdown of the endothelial glycocalyx and
endothelial damage, contributing to fluid extravasation, organ failure and death. Albumin …
endothelial damage, contributing to fluid extravasation, organ failure and death. Albumin …
Pathogenesis of COVID‐19 described through the lens of an undersulfated and degraded epithelial and endothelial glycocalyx
HN du Preez, C Aldous, MR Hayden… - The FASEB …, 2022 - Wiley Online Library
The glycocalyx surrounds every eukaryotic cell and is a complex mesh of proteins and
carbohydrates. It consists of proteoglycans with glycosaminoglycan side chains, which are …
carbohydrates. It consists of proteoglycans with glycosaminoglycan side chains, which are …
N‐Acetylcysteine and Other Sulfur‐Donors as a Preventative and Adjunct Therapy for COVID‐19
The airway epithelial glycocalyx plays an important role in preventing severe acute
respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial …
respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial …
Biomarkers in cardiorenal syndrome and potential insights into novel therapeutics
EYM Chung, K Trinh, J Li, SH Hahn… - Frontiers in …, 2022 - frontiersin.org
Heart and kidney failure often co-exist and confer high morbidity and mortality. The complex
bi-directional nature of heart and kidney dysfunction is referred to as cardiorenal syndrome …
bi-directional nature of heart and kidney dysfunction is referred to as cardiorenal syndrome …
[HTML][HTML] Communication from the Scientific Standardization Committees of the International Society on Thrombosis and Haemostasis on vascular endothelium-related …
Disseminated intravascular coagulation (DIC) is not a disease criterion but a
pathomechanistic process that accompanies various underlying diseases. According to the …
pathomechanistic process that accompanies various underlying diseases. According to the …