Predictive Modelling in pharmacokinetics: from in-silico simulations to personalized medicine
Introduction Pharmacokinetic parameters assessment is a critical aspect of drug discovery
and development, yet challenges persist due to limited training data. Despite advancements …
and development, yet challenges persist due to limited training data. Despite advancements …
Exploring the efficacy of 1-amino-cyclopropane-1-carboxylic acid (ACCA) as a natural compound in strengthening maize resistance against biotic and abiotic stressors …
Objective This study aims to understand plant-bacteria interactions that enhance plant
resistance to environmental stressors, with a focus on maize (Zea mays L.) and its …
resistance to environmental stressors, with a focus on maize (Zea mays L.) and its …
[HTML][HTML] Structure-based discovery of F. religiosa phytochemicals as potential inhibitors against Monkeypox (mpox) viral protein
Outbreaks of Monkeypox (mpox) in over 100 non-endemic countries in 2022 represented a
serious global health concern. Once a neglected disease, mpox has become a global public …
serious global health concern. Once a neglected disease, mpox has become a global public …
[HTML][HTML] Explication of pharmacological proficiency of phytoconstituents from Adansonia digitata Bark: an in vitro and in silico approaches
Compared to other drug discovery sources, traditional medicine has significantly contributed
to developing innovative therapeutic molecules for preventive and curative medicine. The …
to developing innovative therapeutic molecules for preventive and curative medicine. The …
Interplay of precision therapeutics and MD study: Calocybe indica's potentials against cervical cancer and its interaction with VEGF via octadecanoic acid
The evolving landscape of personalized medicine necessitates a shift from traditional
therapeutic interventions towards precision‐driven approaches. Embracing this paradigm …
therapeutic interventions towards precision‐driven approaches. Embracing this paradigm …
[HTML][HTML] Development of newer generation Vascular endothelial growth factor Receptor-2 Inhibitors: Pharmacophore based design, virtual Screening, molecular …
Abstract Vascular Endothelial Growth Factor (VEGF) has a greater impact on
carcinogenesis, and it is the most significant receptor in mediating the mutagenesis and …
carcinogenesis, and it is the most significant receptor in mediating the mutagenesis and …
Molecular dynamics simulations assisted investigation of phytochemicals as potential lead candidates against anti-apoptotic Bcl-B protein
Due to the multifarious nature of cancer, finding a single definitive cure for this dreadful
disease remains an elusive challenge. The dysregulation of the apoptotic pathway or …
disease remains an elusive challenge. The dysregulation of the apoptotic pathway or …
Phytochemical stimulants for cancer therapeutics from Garcinia gummi-gutta: A prime research report
BV Vibala, PK Praseetha, S Vijayakumar - Gene Reports, 2024 - Elsevier
Cancers and tumors grow day by day and alternate traditional-based medicines are in
demand to nullify the toxicity and side effects caused by modern pharmacological …
demand to nullify the toxicity and side effects caused by modern pharmacological …
Identification of Antiviral Drug Candidates Against Monkeypox DNA Polymerase and Profilin-like Protein A42R Utilizing an In-Silico Approach
M Amjid, MM Khan, SF Pastore, JB Vincent… - bioRxiv, 2024 - biorxiv.org
Monkeypox virus (MPXV) is emerging as a major concern in the field of infectious diseases.
Current treatments are limited, highlighting the need for new therapeutic options. The use of …
Current treatments are limited, highlighting the need for new therapeutic options. The use of …
[PDF][PDF] Journal of Biosafety and Biosecurity
RK Mohapatra, A Mahal, PK Mohapatra, AK Sarangi… - 2024 - researchgate.net
abstract Outbreaks of Monkeypox (mpox) in over 100 non-endemic countries in 2022
represented a serious global health concern. Once a neglected disease, mpox has become …
represented a serious global health concern. Once a neglected disease, mpox has become …