Metals to combat antimicrobial resistance

A Frei, AD Verderosa, AG Elliott, J Zuegg… - Nature Reviews …, 2023 - nature.com
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

Spin-vibronic mechanism for intersystem crossing

TJ Penfold, E Gindensperger, C Daniel… - Chemical …, 2018 - ACS Publications
Intersystem crossing (ISC), formally forbidden within nonrelativistic quantum theory, is the
mechanism by which a molecule changes its spin state. It plays an important role in the …

Combination of light and Ru (II) polypyridyl complexes: Recent advances in the development of new anticancer drugs

L Conti, E Macedi, C Giorgi, B Valtancoli… - Coordination Chemistry …, 2022 - Elsevier
The increasing impact of cancer on worldwide mortality makes the research of novel
chemotherapeutic agents a current and challenging issue. In the recent years, transition …

Photoelectrochemical DNA biosensors

WW Zhao, JJ Xu, HY Chen - Chemical reviews, 2014 - ACS Publications
Biosensors could register a biological event and convert it into a measurable signal with
specific biosensing elements and transducers. 1− 5 A DNA biosensor is a device that …

Ruthenium complexes as antimicrobial agents

F Li, JG Collins, FR Keene - Chemical Society Reviews, 2015 - pubs.rsc.org
One of the major advances in medical science has been the development of antimicrobials;
however, a consequence of their widespread use has been the emergence of drug-resistant …

Phosphorescent heavy-metal complexes for bioimaging

Q Zhao, C Huang, F Li - Chemical Society Reviews, 2011 - pubs.rsc.org
The application of phosphorescent heavy-metal complexes with d6, d8 and d10 electron
configurations for bioimaging is a new and promising research field and has been attracting …

Ruthenium (II) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

MR Gill, JA Thomas - Chemical Society Reviews, 2012 - pubs.rsc.org
In the last few decades, coordination complexes based on d6 metal centres and polypyridyl
ligand architectures been developed as structure-and site-specific reversible DNA binding …

Metal complexes as DNA intercalators

HK Liu, PJ Sadler - Accounts of Chemical Research, 2011 - ACS Publications
DNA has a strong affinity for many heterocyclic aromatic dyes, such as acridine and its
derivatives. Lerman in 1961 first proposed intercalation as the source of this affinity, and this …

Application of metal coordination chemistry to explore and manipulate cell biology

KL Haas, KJ Franz - Chemical reviews, 2009 - ACS Publications
Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …

Mass spectrometry of nucleic acid noncovalent complexes

E Largy, A Konig, A Ghosh, D Ghosh… - Chemical …, 2021 - ACS Publications
Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …