The anatomy of the oral and maxillofacial sites is complex, and bone defects caused by
trauma, tumors, and inflammation in these zones are extremely difficult to repair. Among the …

Peptide-based hydrogels are widely studied and applied in bone repair because of their
good biocompatibility, biodegradability and designability. Peptide-based hydrogels can be …

Guided bone regeneration (GBR) is a promising technique in bone tissue engineering that
aims to replace lost or injured bone using resorbable scaffolds. The promotion of osteoblast …

Bone regeneration depends on a pool of bone/cartilage stem/progenitor cells and signaling
mechanisms regulating their differentiation. Using in vitro approach, we have shown that …

Background and objectives In spite of bone's healing capacity, critical-size bone defect
regeneration and peri-implant osseointegration are challenging. Tissue engineering …

Mobilizing endogenous progenitor cells to repair damaged tissue in situ has the potential to
revolutionize the field of regenerative medicine, while the early establishment of a vascular …

Background Icariin (ICA), a main active ingredient of Herba Epimedium, could promote bone
formation, inhibit bone resorption and alleviate inflammatory responses. The aim of this …

Periodontitis is a multifactorial disease that involves the destruction of hard and soft tissues
surrounding the tooth. Routine periodontal treatment includes mechanical debridement …

Background and Objectives: The use of biomaterials in dentistry is extremely common. From
a commercial perspective, different types of osteoconductive and osteoinductive …

Critical bone defects are the result of traumatic, infection-or tumor-induced segmental bone
loss and represent a therapeutic problem that has not been solved by current reconstructive …