Mesenchymal stromal stem cells (MSCs) possess a remarkable potential for numerous
clinical applications due to their unique properties including self-renewal …

Cancer immunotherapy is a groundbreaking strategy that has revolutionized the field of
oncology compared to other therapeutic strategies, such as surgery, chemotherapy, or …

In contrast to conventional anti-tumor agents, nano-carriers allow co-delivery of distinct
drugs in a cell type-specific manner. So far, many nanodrug-based immunotherapeutic …

The dynamic roles of T cells in the immune system to recognize and destroy the infected or
mutated cells render T cell therapy a prospective treatment for a variety of diseases …

Recent clinical successes of chimeric antigen receptor (CAR) T cell therapy have led the
booming of developments in cancer immunotherapy utilizing ex vivo engineered immune …

The expeditious progress of Mesenchymal Stromal Cells (MSC) for therapeutic intervention
calls for means to compare differences in potency of cell products. The differences may be …

Over the last decade, water-soluble polyisocyanopeptides (PICs) have emerged as a new
class of biomimetic polymers. Analogous to biopolymers, PICs exhibit a semi-flexible nature; …

Activation of immune cells is an essential process in innate and adaptive immunity. A high
number of immune cell activation pathways have been discovered, which are stimulated via …

Adoptive cell therapy (ACT) harnesses the capabilities of immune cells to fight complex
diseases such as cancer. Treatment with adoptive transfer of engineered cells has led to …

The ex vivo activation and proliferation of cytotoxic T cells are critical steps in adoptive
immunotherapy. Today, T cells are activated by stimulation with antibody-coated magnetic …