Fluorescent probes for bioimaging of potential biomarkers in Parkinson's disease

L Gao, W Wang, X Wang, F Yang, L Xie… - Chemical Society …, 2021 - pubs.rsc.org
Parkinson's disease (PD), as the second most common neurodegenerative disease, is
caused by complex pathological processes and currently remains very difficult to treat. PD …

[HTML][HTML] Structure and aggregation mechanisms in amyloids

ZL Almeida, RMM Brito - Molecules, 2020 - mdpi.com
The aggregation of a polypeptide chain into amyloid fibrils and their accumulation and
deposition into insoluble plaques and intracellular inclusions is the hallmark of several …

Advances in nanomedicines for diagnosis of central nervous system disorders

X Zhang, J Zhou, Z Gu, H Zhang, Q Gong, K Luo - Biomaterials, 2021 - Elsevier
In spite of a great improvement in medical health services and an increase in lifespan, we
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …

Controlled Growth and Self‐Assembly of Multiscale Organic Semiconductor

L Bai, N Wang, Y Li - Advanced Materials, 2022 - Wiley Online Library
Currently, organic semiconductors (OSs) are widely used as active components in practical
devices related to energy storage and conversion, optoelectronics, catalysis, and biological …

Highly effective inactivation of SARS-CoV-2 by conjugated polymers and oligomers

FA Monge, P Jagadesan, V Bondu… - … applied materials & …, 2020 - ACS Publications
In the present study, we examined the inactivation of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) by synthetic conjugated polymers and oligomers developed in …

Design principles and fundamental understanding of biosensors for amyloid-β detection

Y Zhang, B Ren, D Zhang, Y Liu, M Zhang… - Journal of Materials …, 2020 - pubs.rsc.org
Alzheimer's disease (AD), as an age-related, progressive neurodegenerative disease,
poses substantial challenges and burdens on public health and disease research. While …

Cross-reactive fluorescent sensor array for discrimination of amyloid beta aggregates

P Zhang, C Tan - Analytical Chemistry, 2022 - ACS Publications
It has been hypothesized that misfolding and misassembly of proteins into various
aggregation states contribute to several neurodegenerative diseases. For instance, amyloid …

Alpha‐Synuclein Oligomers Driven T1–T2 Switchable Nanoprobes for Early and Accurate Diagnosis of Parkinson's Disease

Y Chen, Z Liang, Q Wang, L Xiao, S Xie… - Advanced …, 2024 - Wiley Online Library
The alpha‐synuclein (α‐syn) oligomers hold a central role in the pathology of Parkinson's
disease (PD). Achieving accurate detection of α‐syn oligomers in vivo presents a promising …

Small molecule-based fluorescent probes for the detection of α-Synuclein aggregation states

R Haque, D Maity - Bioorganic & Medicinal Chemistry Letters, 2023 - Elsevier
The formation of aggregates due to protein misfolding is encountered in various
neurodegenerative diseases. α-Synuclein (α-Syn) aggregation is linked to Parkinson's …

Influence of hydrophobic interfaces and shear on ovalbumin amyloid-like fibril formation in oil-in-water emulsions

AMR Huyst, LJ Deleu, T Luyckx, MA Lambrecht… - Food …, 2021 - Elsevier
Animal proteins are widely used because of their good techno-functional (eg emulsification)
properties. However, the large ecological impact of animal-derived proteins is often debated …