Clinical significance and inflammatory landscapes of a novel recurrence-associated immune signature in early-stage lung adenocarcinoma

C Zhang, Z Zhang, G Zhang, Z Zhang, Y Luo, F Wang… - Cancer letters, 2020 - Elsevier
The prevalence of early-stage lung adenocarcinoma (LUAD) has increased alongside
increased implementation of lung cancer screenings. Robust discrimination criteria are …

Identification of a novel cell cycle‐related gene signature predicting survival in patients with gastric cancer

L Zhao, L Jiang, L He, Q Wei, J Bi… - Journal of cellular …, 2019 - Wiley Online Library
Gastric cancer (GC) is one of the most fatal cancers in the world. Thousands of biomarkers
have been explored that might be related to survival and prognosis via database mining …

Identification of novel cell glycolysis related gene signature predicting survival in patients with endometrial cancer

ZH Wang, YZ Zhang, YS Wang, XX Ma - Cancer cell international, 2019 - Springer
Background Endometrial cancer (EC) is one of the three major gynecological malignancies.
Numerous biomarkers that may be associated with survival and prognosis have been …

Predicting clinical outcomes of cancer patients with a p53 deficiency gene signature

E Schaafsma, EM Takacs, S Kaur, C Cheng… - Scientific reports, 2022 - nature.com
The tumor suppressor p53, encoded by the TP53 gene, is mutated or nullified in nearly 50%
of human cancers. It has long been debated whether TP53 mutations can be utilized as a …

Recurrence after complete resection for non-small cell lung cancer in the National Lung Screening Trial

AL Potter, CL Costantino, RA Suliman… - The Annals of Thoracic …, 2023 - Elsevier
Background The objective of this study was to evaluate patterns, predictors, and long-term
outcomes of recurrent disease after complete resection for early-stage non-small cell lung …

Single-cell RNA sequencing reveals the impact of chromosomal instability on glioblastoma cancer stem cells

Y Zhao, R Carter, S Natarajan, FS Varn… - BMC medical …, 2019 - Springer
Background Intra-tumor heterogeneity stems from genetic, epigenetic, functional, and
environmental differences among tumor cells. A major source of genetic heterogeneity …

Identification of SPP1 as a promising biomarker to predict clinical outcome of lung adenocarcinoma individuals

S Li, R Yang, X Sun, S Miao, T Lu, Y Wang, Y Wo… - Gene, 2018 - Elsevier
We identified and investigated the prognostic value of secreted phosphoprotein 1 (SPP1) in
lung adenocarcinoma (LUAD) patients and evaluate the relationship between the SPP1 …

Gene signature‐based prediction of triple‐negative breast cancer patient response to Neoadjuvant chemotherapy

Y Zhao, E Schaafsma, C Cheng - Cancer Medicine, 2020 - Wiley Online Library
Neoadjuvant chemotherapy is the current standard of care for large, advanced, and/or
inoperable tumors, including triple‐negative breast cancer. Although the clinical benefits of …

Identification of a novel gene pairs signature in the prognosis of gastric cancer

PL Peng, XY Zhou, GD Yi, PF Chen, F Wang… - Cancer …, 2018 - Wiley Online Library
Current prognostic signatures need to be improved in identifying high‐risk patients of gastric
cancer (GC). Thus, we aimed to develop a reliable prognostic signature that could assess …

Genotype-to-phenotype associations in the aggressive variant prostate cancer molecular profile (AVPC-m) components

R Soundararajan, P Viscuse, P Pilie, J Liu, S Logotheti… - Cancers, 2022 - mdpi.com
Simple Summary We treat prostate cancer like it is one disease, but it is clear that it behaves
like different diseases in different patients, with some having excellent responses to …