There is an urgent need to identify novel therapies for childhood cancers. Neuroblastoma is
the most common pediatric solid tumor, and accounts for~ 15% of childhood cancer‐related …

Survivin is the smallest member of the inhibitor of apoptosis protein family, which has key
roles in regulating cell division and inhibiting apoptosis by blocking caspase activation …

Evasion of apoptosis is considered to be one of the hallmarks of human cancers. This cell
death modality is executed by caspases and several upstream regulatory factors, which …

Simple Summary The Inhibitor of Apoptosis (IAP) family of proteins has emerged as a
potential pharmacological target in cancer. Abnormal expression of IAPs can lead to …

Simple Summary When tumors become resistant to chemotherapeutics, alternative
treatment strategies must be explored. Gene targeting provides a personalized and …

Abstract Gold nanoparticles (Au NPs) assembled through Au− S covalent bonds have been
widely used in biomolecule‐sensing technologies. However, during the process, detection …

X-linked inhibitor of apoptosis protein (XIAP), survivin, and BRUCE are members of the
inhibitor-of-apoptosis protein (IAP) family known for their inhibitory effects on caspase …

Protein diversity due to alternative mRNA splicing or post-translational modifications (PTMs)
plays a vital role in various cellular functions. The mitotic kinases polo-like kinase 1 (PLK1) …

Survivin has multiple functions including cytoprotection, inhibition of cell death, and cell‐
cycle regulation, especially at the mitotic process stage, all of which favor cancer survival …

Combined treatment with quercetin and TRAIL induced cytotoxicity and enhanced annexin V
staining and poly (ADP-ribose) polymerase (PARP) cleavage in human prostate cancer cell …