Nanomedicines employ multiple endocytic pathways to enter cells. Their following fate is
interesting, but it is not sufficient understood currently. This review introduces the endocytic …

Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …

Introduction: Current drugs for the treatment of psychiatric or neurodegenerative disorders
have limitations. Psychotherapeutic drugs such as typical and atypical antipsychotics …

During entry, human papillomavirus (HPV) traffics from the cell surface to the endosome and
then to the trans-Golgi network (TGN) and Golgi apparatus. HPV must transit across the …

The protein composition of the Golgi is intimately linked to its structure and function. As the
Golgi serves as the major protein-sorting hub for the secretory pathway, it faces the unique …

Tandem affinity purification (TAP) is a methodology for the isolation of protein complexes
from endogenous sources. It involves incorporation of a dual-affinity tag into the protein of …

The cardiac membrane protein phospholamban (PLN) is targeted by protein kinase A (PKA)
at Ser16 and by Ca2+/calmodulin-dependent protein kinase II (CaMKII) at Thr17. β …

Sigma receptors (σRs) are structurally unique proteins that function intracellularly as
chaperones. Historically, σRs have been implicated as modulators of psychomotor stimulant …

To investigate the mechanism of regulation of sarco-endoplasmic reticulum Ca 2+-ATPase
(SERCA) by phospholamban (PLB), we expressed Cerulean-SERCA and yellow fluorescent …

α-Crystallin B (cryAB) is the most abundant small heat shock protein in cardiomyocytes
(CMs) and has been shown to have potent antiapoptotic properties. Because the …