Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii

CO Vrancianu, I Gheorghe, IB Czobor, MC Chifiriuc - Microorganisms, 2020 - mdpi.com
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry,
environment and societal development. One of the most important pathogens responsible …

CRISPR-Based Gene Editing in Acinetobacter baumannii to Combat Antimicrobial Resistance

M Junaid, K Thirapanmethee, P Khuntayaporn… - Pharmaceuticals, 2023 - mdpi.com
Antimicrobial resistance (AMR) poses a significant threat to the health, social, environment,
and economic sectors on a global scale and requires serious attention to addressing this …

CRISPR/Cas-mediated knockdown of vacuolar invertase gene expression lowers the cold-induced sweetening in potatoes

A Yasmeen, S Shakoor, S Azam, A Bakhsh, N Shahid… - Planta, 2022 - Springer
Main conclusion VInv gene editing in potato using CRISPR/Cas9 resulted in knockdown of
expression and a lower VInv enzymatic activity resulting in a decrease in post-harvest cold …

CRISPR-cas, a revolution in the treatment and study of ESKAPE infections: pre-clinical studies

M González de Aledo, M González-Bardanca, L Blasco… - Antibiotics, 2021 - mdpi.com
One of the biggest threats we face globally is the emergence of antimicrobial-resistant
(AMR) bacteria, which runs in parallel with the lack in the development of new …

CRISPR in modulating antibiotic resistance of ESKAPE pathogens

U Saha, R Gondi, A Patil, SD Saroj - Molecular Biotechnology, 2023 - Springer
Abstract The ESKAPE (Enterococcus spp., Staphylococcus aureus, Klebsiella pneumoniae,
Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) isolates both …

[HTML][HTML] The prominent characteristics of the effective sgRNA for a precise CRISPR genome editing

R Mohammadhassan, S Tutunchi… - CRISPR Technology …, 2022 - intechopen.com
Clustered regularly interspaced short palindromic repeats (CRISPRs) technique is the most
effective and novelist technique for genome editing. CRISPR mechanism has been widely …

Recent Advances in Genetic Tools for Acinetobacter baumannii

EME Sykes, S Deo, A Kumar - Frontiers in Genetics, 2020 - frontiersin.org
Acinetobacter baumannii is classified as a top priority pathogen by the World Health
Organization (WHO) because of its widespread resistance to all classes of antibiotics. This …

Cell and gene therapies for mucopolysaccharidoses: base editing and therapeutic delivery to the CNS

CL Christensen, RE Ashmead, FYM Choy - Diseases, 2019 - mdpi.com
Although individually uncommon, rare diseases collectively account for a considerable
proportion of disease impact worldwide. A group of rare genetic diseases called the …

[HTML][HTML] Design of Specific and Efficient sgRNA for CRISPR/Cas9 System to Knockout Superoxide Dismutase 2 in Breast Cancer Stem Cells

S Arumsari, SI Wanandi, RA Syahrani… - International Journal …, 2024 - ijtech.eng.ui.ac.id
Design of Specific and Efficient sgRNA for CRISPR/Cas9 System to Knockout Superoxide
Dismutase 2 in Breast Cancer Stem Cells title Title Author Issue Keywords Current Issue : Vol …

[PDF][PDF] Design of CRISPR-based Targets for the Development of a Diagnostic Method for SARS-CoV-2: an in Silico Approach

AP Karlapudi, CV Thirupati, K Srirrama… - Eurasian Journal of …, 2020 - academia.edu
Objectives: To computationally design CRISPR target-based Single-guided RNA (sg RNA)
for the development of a diagnostic method for SARS-CoV-2. Methods: In the present study …