Abstract Background and Objective The prevalence of dementia is increasing, while new
opportunities for diagnosing, treating and possibly preventing Alzheimer's disease and other …

Background The irreversibility of cognitive impairment of Alzheimer's disease (AD) prompts
that preventing or delaying the onset of AD should be a public health priority. Vitamin B …

Alzheimer's disease (AD), like other multifactorial diseases, is the result of a systemic
breakdown of different physiological networks. As result, several lines of evidence suggest …

Introduction: Alzheimer's disease (AD) is a slow, irreversible, progressive, complex, and fatal
neurodegenerative disorder. Available pharmacological treatment, known for almost two …

Background Caregiver burden is related to personal factors and patient characteristics and
is greater when neuropsychiatric symptoms (NPSs) are present. Objective: Estimate the …

Background China has the largest number of dementia patients worldwide. The prolonged
course of dementia has a serious negative impact on the economy and quality of life of …

Introduction The increasing prevalence of Alzheimer's disease and related dementias
(ADRD) presents both a burden and an opportunity for intervention. This study aims to …

Alzheimer's disease (AD), an ongoing neurodegenerative disorder among the elderly, is
signalized by amnesia, progressive deficiency in cognitive roles, and behavioral deformity …

Background Alzheimer's disease (AD) is a very disabling long-term disease that requires
continuous regular care. A cost-effective and sustainable means of such care may be …

Optimization and re-optimization of bioactive molecules using in silico methods have found
application in the design of more active ones. Herein, we applied a pharmacophore …