Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Metabolomics and lipidomics are new drivers of the omics era as molecular signatures and
selected analytes allow phenotypic characterization and serve as biomarkers, respectively …

The separation and detection of isomers remains a challenge for many areas of mass
spectrometry. This article highlights laser photodissociation and ion mobility strategies that …

The difference in functionality of many isomeric biomolecules requires their analytical
identification for life science studies. We present a universal approach for quantitative …

Despite the popularity of ion mobility spectrometry (IMS) for glycan analysis, its limited
structural resolution hinders the effective separation of many glycan isomers. This leads to …

The tremendous structural and isomeric diversity of lipids enables a wide range of their
functions in nature but makes the identification of these biomolecules challenging. We …

Monitoring the level of hydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) in urine is
the key to exploring human metabolic changes and comprehensive potential toxicity of …

Lipids are small but complex biomolecules that feature an immense structural and functional
diversity. The molecular structure and biological functions of lipids are intricately linked …

Characterization of carbohydrate structures using mass spectrometry is a challenging task.
Understanding the dissociation mechanisms of carbohydrates in the gas phase is crucial for …

Enantiomers of a lipid erythro-sphingosine have been quantified with≈ 4% accuracy by UV
cold ion spectroscopy of their non-covalent complexes with a chiral aromatic molecule. The …