Throughout our lifespan, new sensory experiences and learning continually shape our
neuronal circuits to form new memories. Plasticity at the level of synapses has been …

The brain changes as we age and these changes are associated with functional
deterioration and neurodegenerative disease. It is vital that we better understand individual …

Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

The synapse is the focus of experimental research and theory on the cellular mechanisms of
nervous system plasticity and learning, but recent research is expanding the consideration …

Quantifying the microstructural properties of the human brain's connections is necessary for
understanding normal ageing and disease. Here we examine brain white matter magnetic …

Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

FreeSurfer is a suite of tools for the analysis of neuroimaging data that provides an array of
algorithms to quantify the functional, connectional and structural properties of the human …

We present a review of the characterization of healthy brain aging using MRI with an
emphasis on morphology, lesions, and quantitative MR parameters. A scope review found …

Cognition arises as a result of coordinated processing among distributed brain regions and
disruptions to communication within these neural networks can result in cognitive …

Although connections between cognitive deficits and age-associated brain differences have
been elucidated, relationships with motor performance are less well understood. Here, we …