Macrophages play an important role in tissue homeostasis, tissue remodeling, immune
response, and progression of cancer. Consequently, macrophages exhibit significant …

Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

The Natural Cytotoxicity Receptors (NCRs), NKp46, NKp44, and NKp30, were some of the
first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted …

Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

WNT/β-catenin signaling is involved in many physiological processes. Its implication in
embryonic development, cell migration, and polarization has been shown. Nevertheless …

Natural killer (NK) cells can induce an antigen-independent immune response against
malignant cells. A growing number of scientific reports and clinical studies have shown …

Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Rationale The liver-specific natural killer (NK) cell population is critical for local innate
immune responses, but the mechanisms that lead to their selective homing and the …

Immune cells, as a consequence of their plasticity, can acquire altered phenotype/functions
within the tumor microenvironment (TME). Some of these aberrant functions include …

Mesenchymal stromal cells (MSCs) support hematopoiesis and exert immunoregulatory
activities. Here, we analyzed the functional outcome of the interactions between MSCs and …