The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

Recent studies have demonstrated prominent and widespread movement-related signals in
the brain of head-fixed mice, even in primary sensory areas. However, it is still unknown …

The light microscope is traditionally an instrument of substantial size and expense. Its
miniaturized integration would enable many new applications based on mass-producible …

The transmission of the heartbeat through the cerebral vascular system causes intracranial
pressure pulsations. We discovered that arterial pressure pulsations can directly modulate …

Sensation is an active process involving the sampling and central processing of external
stimuli selectively in space and time. Olfaction in particular depends strongly on active …

Widefield imaging of calcium dynamics is an emerging method for mapping regional neural
activity but is currently limited to restrained animals. Here we describe cScope, a head …

INTRODUCTION Advances in monitoring brain activity at large and fine scales have
revealed tremendous complexity in how the brain responds to, and represents, the external …

Historically, the human sense of smell has been regarded as the odd stepchild of the
senses, especially compared to the sensory bravado of seeing, touching, and hearing. The …

It has been proposed that a single sniff generates a" snapshot" of the olfactory world.
However, odor coding on this timescale is poorly understood, and it is not known whether …

Rhythmic neural activity is a hallmark of brain function, used ubiquitously to structure neural
information. In mammalian olfaction, repetitive sniffing sets the principal rhythm but little is …