Abdominal aortic aneurysm: update on pathogenesis and medical treatments

J Golledge - Nature Reviews Cardiology, 2019 - nature.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

Cellular mechanisms of aortic aneurysm formation

RA Quintana, WR Taylor - Circulation research, 2019 - Am Heart Assoc
Aortic aneurysms are a common vascular disease in Western populations that can involve
virtually any portion of the aorta. Abdominal aortic aneurysms are much more common than …

Editor's choice–European Society for Vascular Surgery (ESVS) 2019 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms

A Wanhainen, F Verzini, I Van Herzeele… - European Journal of …, 2019 - ejves.com
Members of this Guideline Writing Committee (GWC) were selected by the European Society
for Vascular Surgery (ESVS) to represent physicians involved in the management of patients …

Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm

S Jana, M Hu, M Shen, Z Kassiri - Experimental & molecular medicine, 2019 - nature.com
Aortic aneurysm is an asymptomatic disease with dire outcomes if undiagnosed. Aortic
aneurysm rupture is a significant cause of death worldwide. To date, surgical repair or …

JCS/JSCVS/JATS/JSVS 2020 guideline on diagnosis and treatment of aortic aneurysm and aortic dissection

H Ogino, O Iida, K Akutsu, Y Chiba, H Hayashi… - Circulation …, 2023 - jstage.jst.go.jp
Of the clinical practice guideline of the Japanese Circulation Society concerning aortic
diseases, the Guidelines on Diagnosis and Treatment of Aortic Dissection (first edition) were …

Genetic and epigenetic mechanisms underlying vascular smooth muscle cell phenotypic modulation in abdominal aortic aneurysm

R Gurung, AM Choong, CC Woo, R Foo… - International journal of …, 2020 - mdpi.com
Abdominal aortic aneurysm (AAA) refers to the localized dilatation of the infra-renal aorta, in
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …

Effect of doxycycline on aneurysm growth among patients with small infrarenal abdominal aortic aneurysms: a randomized clinical trial

BT Baxter, J Matsumura, JA Curci, R McBride… - Jama, 2020 - jamanetwork.com
Importance Abdominal aortic aneurysms affect more than 3% of US older adults. Objective
To test whether doxycycline reduces the growth of abdominal aortic aneurysm over 2 years …

Primary care screening for abdominal aortic aneurysm: updated evidence report and systematic review for the US Preventive Services Task Force

JM Guirguis-Blake, TL Beil, CA Senger, EL Coppola - Jama, 2019 - jamanetwork.com
Importance Ruptured abdominal aortic aneurysms (AAAs) have mortality estimated at 81%.
Objective To systematically review the evidence on benefits and harms of AAA screening …

Abdominal aortic aneurysms

J Anagnostakos, BK Lal - Progress in cardiovascular diseases, 2021 - Elsevier
Abdominal aortic aneurysms (AAA) are prevalent among older adults and can cause
significant morbidity and mortality if not addressed in a timely fashion. Their etiology remains …

Pathogenesis and management of abdominal aortic aneurysm

J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …