Recovery from bone, osteochondral, and cartilage injuries/diseases has been burdensome
owing to the damaged vasculature of large defects and/or avascular nature of cartilage …

Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …

Cells and organelles are delimited by lipid bilayers in which high deformability is essential to
many cell processes, including motility, endocytosis and cell division. Membrane tension is …

Although the shapes of organisms are encoded in their genome, the developmental
processes that lead to the final form of vertebrates involve a constant feedback between …

Evidence from physical sciences in oncology increasingly suggests that the interplay
between the biophysical tumor microenvironment and genetic regulation has significant …

The fluid-mosaic model posits a liquid-like plasma membrane, which can flow in response to
tension gradients. It is widely assumed that membrane flow transmits local changes in …

The extracellular matrix (ECM) harbours various signals to control cellular functions and the
materiality of tissues. Most efforts to synthetically reconstitute the matrix by biomaterial …

Membrane tension is thought to be a long-range integrator of cell physiology. Membrane
tension has been proposed to enable cell polarity during migration through front-back …

Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …

Many cell phenomena that involve shape changes are affected by the intrinsic deformability
of the plasma membrane (PM). Far from being a passive participant, the PM is now known to …