Importance Multiple sclerosis (MS) is an autoimmune-mediated neurodegenerative disease
of the central nervous system characterized by inflammatory demyelination with axonal …

The factor that is most relevant and strongly associated with the clinical course of multiple
sclerosis is chronological age. Very young patients exclusively have relapsing remitting …

There are over 15 disease-modifying drugs that have been approved over the last 20 years
for the treatment of relapsing–remitting multiple sclerosis (MS), but there are limited …

Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system that
causes significant disability and healthcare burden. The treatment of MS has evolved over …

Immunoassays are powerful qualitative and quantitative analytical techniques. Since the first
description of an immunoassay method in 1959, advances have been made in assay …

Using a philosophical approach or deductive reasoning, we challenge the dominant clinico-
radiological worldview that defines multiple sclerosis (MS) as a focal inflammatory disease …

Background: Multiple sclerosis (MS) is a multifocal inflammatory central nervous system
disorder. There are now many highly effective disease-modifying therapies (DMTs) available …

Many challenges exist in the precise diagnosis and clinical management of secondary
progressive multiple sclerosis (SPMS) because of the lack of definitive clinical, imaging …

Myelin is the lipid-rich structure formed by oligodendrocytes (OLs) that wraps the axons in
multilayered sheaths, assuring protection, efficient saltatory signal conduction and metabolic …

Abstract Purpose of Review In this review, we provide a comprehensive update on current
scientific advances and emerging therapeutic approaches in the field of multiple sclerosis …