The effect of NSAIDs on spinal fusion: a cross-disciplinary review of biochemical, animal, and human studies
Purpose Non-steroidal anti-inflammatory drugs (NSAIDs) play an important role in
postoperative pain management. However, their use in the setting of spine fusion surgery …
postoperative pain management. However, their use in the setting of spine fusion surgery …
Influence of pain and analgesia on orthopedic and wound-healing models in rats and mice
MK Huss, SA Felt, C Pacharinsak - Comparative Medicine, 2019 - ingentaconnect.com
The surgical stress response and resulting physiologic changes can lead to postoperative
complications and negatively impact animal welfare. Although appropriate pain …
complications and negatively impact animal welfare. Although appropriate pain …
Effect of NSAID use on bone healing in pediatric fractures: a preliminary, prospective, randomized, blinded study
JAV Nuelle, KM Coe, HA Oliver, JL Cook… - Journal of Pediatric …, 2020 - journals.lww.com
Background: This study aimed to investigate if nonsteroidal anti-inflammatory drugs
(NSAIDs) used in the acute phase of bone healing in children with fractures result in delayed …
(NSAIDs) used in the acute phase of bone healing in children with fractures result in delayed …
Non-steroidal anti-inflammatory drugs and bone healing in animal models—a systematic review and meta-analysis
H Al-Waeli, AP Reboucas, A Mansour, M Morris… - Systematic …, 2021 - Springer
Background Non-steroidal anti-inflammatory drugs (NSAID) have excellent anti-
inflammatory and analgesic properties and are extensively used to treat post-traumatic or …
inflammatory and analgesic properties and are extensively used to treat post-traumatic or …
Synthesis, spectroscopic and thermal studies of Mg (II), Ca (II), Sr (II) and Ba (II) diclofenac sodium complexes as anti-inflammatory drug and their protective effects on …
The main task of our present study is the preparation of newly complexes of Mg (II), Ca (II),
Sr (II) and Ba (II) with diclofenac which succeeded to great extent in alleviating the side …
Sr (II) and Ba (II) with diclofenac which succeeded to great extent in alleviating the side …
Nonsteroidal anti-inflammatory drugs in the acute post-operative period are associated with an increased incidence of pseudarthrosis, hardware failure, and revision …
SE Lindsay, T Philipp, WHA Ryu, C Wright, J Yoo - Spine, 2023 - journals.lww.com
Study Design. Retrospective study. Summary of Background Data. Research has shown that
the use of NSAIDs and COX-2 inhibitors increases the risk of pseudoarthrosis following …
the use of NSAIDs and COX-2 inhibitors increases the risk of pseudoarthrosis following …
Adjuvant drug-assisted bone healing: Part I–Modulation of inflammation
R Rothe, S Schulze, C Neuber… - Clinical …, 2019 - content.iospress.com
Critical-size bone defects after compound fractures, infection, or tumor resection are
challenging to treat. The same is true for fractures in patients with impaired bone healing …
challenging to treat. The same is true for fractures in patients with impaired bone healing …
Internet pseudoscience: Testing opioid containing formulations with tampering potential
JP Pascali, P Fais, F Vaiano, N Pigaiani… - … of Pharmaceutical and …, 2018 - Elsevier
Drug tampering practices, with the aim to increase availability of drug delivery and/or
enhance drug effects, are accessible on Internet and are practiced by some portion of …
enhance drug effects, are accessible on Internet and are practiced by some portion of …
Biotransformation and oxidative stress responses in rat hepatic cell-line (H4IIE) exposed to racemic ketoprofen (RS-KP) and its enantiomer, dexketoprofen (S (+)-KP)
Pharmaceuticals such as racemate ketoprofen (RS-KP) and its enantiomer, dexketoprofen
(S (+)-KP) are highly detectable non-steroidal anti-inflammatory drugs (NSAIDs) in the …
(S (+)-KP) are highly detectable non-steroidal anti-inflammatory drugs (NSAIDs) in the …
Comparison of analgesic efficacy of ibuprofen and dexketoprofen in pain management of long bone fractures: a prospective, randomized, double-blind study
Methods Conducted between August 10, 2023, and January 17, 2024, the study included
100 eligible patients randomized into Dex and Ibu groups. Visual analog scale (VAS) scores …
100 eligible patients randomized into Dex and Ibu groups. Visual analog scale (VAS) scores …