The dual roles of immunity in ALS: injury overrides protection

BJ Murdock, DE Bender, BM Segal, EL Feldman - Neurobiology of disease, 2015 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease
affecting motor neurons. Disease progression is accompanied by a multi-phased immune …

Dendritic cells in the host response to implanted materials

BG Keselowsky, JS Lewis - Seminars in immunology, 2017 - Elsevier
The role of dendritic cells (DCs) and their targeted manipulation in the body's response to
implanted materials is an important and developing area of investigation, and a large …

CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells

G Hartmann, GJ Weiner… - Proceedings of the …, 1999 - National Acad Sciences
DNA molecules containing unmethylated CpG-dinucleotides in particular base contexts
(“CpG motifs”) are excellent adjuvants in rodents, but their effects on human cells have been …

BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis

F Sahm, D Capper, M Preusser, J Meyer… - Blood, The Journal …, 2012 - ashpublications.org
Langerhans cell histiocytosis (LCH) is a clinically and histologically heterogeneous disorder.
Its classification as either reactive inflammatory or neoplastic has been a matter of debate …

Phase I study in melanoma patients of a vaccine with peptide‐pulsed dendritic cells generated in vitro from CD34+ hematopoietic progenitor cells

A Mackensen, B Herbst, JL Chen… - … journal of cancer, 2000 - Wiley Online Library
Dendritic cells (DCs) are professional antigen‐presenting cells (APCs) that can be used for
vaccination purposes, to induce a specific T‐cell response in vivo against melanoma …

Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage

MS Labeur, B Roters, B Pers, A Mehling… - The Journal of …, 1999 - journals.aai.org
Bone marrow-derived dendritic cells (BmDC) are potent APC and can promote antitumor
immunity in mice when pulsed with tumor Ag. This study aimed to define the culture …

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes

M Mesel-Lemoine, J Millet, PO Vidalain, H Law… - Journal of …, 2012 - Am Soc Microbiol
Human coronaviruses are associated with upper respiratory tract infections that occasionally
spread to the lungs and other organs. Although airway epithelial cells represent an …

Development of minimal lentivirus vectors derived from simian immunodeficiency virus (SIVmac251) and their use for gene transfer into human dendritic cells

PE Mangeot, D Nègre, B Dubois, AJ Winter… - Journal of …, 2000 - Am Soc Microbiol
Lentivirus-derived vectors are very promising gene delivery systems since they are able to
transduce nonproliferating differentiated cells, while murine leukemia virus-based vectors …

Efficacy of a dual-epitope dendritic cell vaccine as part of combined immunotherapy for HER2-expressing breast tumors

BG Vincent, DM File, KP McKinnon… - The Journal of …, 2023 - journals.aai.org
Previous work from our group and others has shown that patients with breast cancer can
generate a T cell response against specific human epidermal growth factor 2 (HER2) …

Activity of interleukin 6 in the differentiation of monocytes to macrophages and dendritic cells

H Mitani, N Katayama, H Araki, K Ohishi… - British journal of …, 2000 - Wiley Online Library
Peripheral blood monocytes are common precursor cells of dendritic cells (DCs) and
macrophages. We have searched for factors with the potential to regulate the differentiation …