Lipid-based nanoparticles for drug/gene delivery: An overview of the production techniques and difficulties encountered in their industrial development

M Mehta, TA Bui, X Yang, Y Aksoy, EM Goldys… - ACS Materials …, 2023 - ACS Publications
Over the past decade, the therapeutic potential of nanomaterials as novel drug delivery
systems complementing conventional pharmacology has been widely acknowledged …

Lipid nanocarrier-based drug delivery systems: therapeutic advances in the treatment of lung cancer

SJ Kim, N Puranik, D Yadav, JO Jin… - International Journal of …, 2023 - Taylor & Francis
Although various treatments are currently being developed, lung cancer still has a very high
mortality rate. Moreover, while various strategies for the diagnosis and treatment of lung …

Compritol-based nanostrucutured lipid carriers (NLCs) for augmentation of zolmitriptan bioavailability via the transdermal route: in vitro optimization, ex vivo …

DH Hassan, JN Shohdy, DA El-Setouhy… - Pharmaceutics, 2022 - mdpi.com
Migraine is a severe neurovascular disease manifested mainly as unilateral throbbing
headaches. Triptans are agonists for serotonin receptors. Zolmitriptan (ZMP) is a …

Effects of phospholipid structure on the acoustic cavitation of functionalized mesoporous silica nanoparticles: implications for image-guided drug delivery

TB Alina, HB Kirkpatrick, NM Bower… - ACS Applied Nano …, 2023 - ACS Publications
This study investigates the acoustic response of phospholipid-coated, hydrophobically
modified mesoporous silica nanoparticles (PL-HMSNs) for image-guided drug delivery. PL …

Design, development, evaluation, and in vivo performance of buccal films embedded with paliperidone-loaded nanostructured lipid carriers

FM AlMulhim, AB Nair, B Aldhubiab, H Shah, J Shah… - Pharmaceutics, 2023 - mdpi.com
The therapeutic effectiveness of paliperidone in the treatment of schizophrenia has been
limited by its poor oral bioavailability; hence, an alternative route could be appropriate. This …

Emu oil enriched nanostructured lipid carriers of lornoxicam burdened polymeric gel augmented drug delivery and assisted cartilage repairing in knee osteoarthritis: In …

A Bhosale, VGSS Jyothi, P Devangan, G Bajad… - Journal of Drug Delivery …, 2024 - Elsevier
Lornoxicam (LRX) alleviates pain and inflammation associated with knee osteoarthritis
(OAS). However, inadequate solubility, short half-life, and gastrointestinal side-effects on …

Dependence of the Core–Shell Structure on the Lipid Composition of Nanostructured Lipid Carriers: Implications for Drug Carrier Design

N Izza, N Watanabe, Y Okamoto, K Suga… - ACS Applied Nano …, 2022 - ACS Publications
Nanostructured lipid carriers (NLCs) are a new generation of lipid vectors for drug delivery
systems (DDSs), which are composed of solid and liquid lipids dispersed throughout the …

A Quantitative Approach to Characterize the Surface Modification on Nanoparticles Based on Localized Dielectric Environments

T Mochizuki, S Sampei, K Suga, K Watanabe… - Analytical …, 2024 - ACS Publications
Nanoparticles (NPs) are utilized for the functionalization of composite materials and
nanofluids. Although oxide NPs (eg, silica (SiO2)) exhibit less dispersibility in organic …

Lipid nanoparticle steric stabilization roadmap

X Cai, J Zhai, N Tran, X Mulet, CJ Drummond - Advances in Biomembranes …, 2022 - Elsevier
Lipid nanoparticles, such as liposomes, cubosomes, hexosomes, solid lipid nanoparticles
and nanostructured lipid carriers, have grown in popularity in many biomedical applications …

Vine cane compounds to prevent skin cells aging through solid lipid nanoparticles

A Pereira, MJ Ramalho, R Silva, V Silva… - Pharmaceutics, 2022 - mdpi.com
The long lifespan of the world's population has been raising interest in the research for new
solutions to delay the aging process. With the aim of skin aging prevention, solid lipid …