Performance in athletic activities that include a significant aerobic component at mild or
moderate altitudes shows a large individual variation. Physiologically, a large portion of the …

During exercise, healthy individuals are able to maintain arterial oxygenation, whereas
highly-trained endurance athletes may exhibit an exercise-induced arterial hypoxaemia …

To unravel the mechanisms by which maximal oxygen uptake (V˙ o 2 max) is reduced with
severe acute hypoxia in humans, nine Danish lowlanders performed incremental cycle …

Species that maintain aerobic metabolism when the oxygen (O2) supply is limited represent
ideal models to examine the mechanisms underlying tolerance to hypoxia. The repetitive …

Abstract Calbet, José, and Carsten Lundby. High Alt. Med. & Biol. 10.123–134, 2009.—
Hypoxia-induced hyperventilation is critical to improve blood oxygenation, particularly when …

In young, healthy people the alveolar–arterial P difference (A‐aDO2) is small at rest, but
frequently increases during exercise. Previously, investigators have focused on …

Peak aerobic power in humans () is markedly affected by inspired O2 tension (). The
question to be answered in this study is what factor plays a major role in the limitation of …

Lung diffusing capacity (D l) for carbon monoxide (D lco), nitric oxide (D lno) or oxygen (D lo
2) increases from rest to peak exercise without reaching an upper limit; this recruitment …

As the first step in the oxygen-transport chain, the lung has a critical task: optimizing the
exchange of respiratory gases to maintain delivery of oxygen and the elimination of carbon …

Arterial desaturation during exercise is common in endurance‐trained athletes, a
phenomenon often more pronounced when the muscle mass engaged in the exercise is …