Bioactive inorganic nanomaterials for cancer theranostics
Z Pei, H Lei, L Cheng - Chemical Society Reviews, 2023 - pubs.rsc.org
Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …
biological response or regulate biological functions, thus achieving a better curative effect …
Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy
B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
Engineering nanomedicine for glutathione depletion-augmented cancer therapy
Y Xiong, C Xiao, Z Li, X Yang - Chemical Society Reviews, 2021 - pubs.rsc.org
Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …
Recent advances in nanomaterial‐based nanoplatforms for chemodynamic cancer therapy
SL Li, P Jiang, FL Jiang, Y Liu - Advanced Functional Materials, 2021 - Wiley Online Library
Triggered by the endogenous chemical energy in the tumor microenvironment (TME),
chemodynamic therapy (CDT) as an emerging non‐exogenous stimulant therapeutic …
chemodynamic therapy (CDT) as an emerging non‐exogenous stimulant therapeutic …
Glutathione-depleting nanomedicines for synergistic cancer therapy
X Cheng, HD Xu, HH Ran, G Liang, FG Wu - ACS nano, 2021 - ACS Publications
Cancer cells frequently exhibit resistance to various molecular and nanoscale drugs, which
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
A “closed‐loop” therapeutic strategy based on mutually reinforced ferroptosis and immunotherapy
Y Du, R Zhang, J Yang, S Liu, J Zhou… - Advanced Functional …, 2022 - Wiley Online Library
The immunosuppression and immune escape of current immunotherapy result in low
efficacy, and ferroptosis is greatly restricted by the low reactive oxygen species (ROS) …
efficacy, and ferroptosis is greatly restricted by the low reactive oxygen species (ROS) …
Fe3O4/Ag/Bi2MoO6 Photoactivatable Nanozyme for Self‐Replenishing and Sustainable Cascaded Nanocatalytic Cancer Therapy
C Cao, H Zou, N Yang, H Li, Y Cai, X Song… - Advanced …, 2021 - Wiley Online Library
Catalytic cancer therapy based on nanozymes has recently attracted much interest.
However, the types of the current nanozymes are limited and their efficiency is usually …
However, the types of the current nanozymes are limited and their efficiency is usually …
A metabolic multistage glutathione depletion used for tumor-specific chemodynamic therapy
The high glutathione (GSH) content in tumor cells strongly affects the efficiency of
chemodynamic therapy (CDT). Despite devoted efforts, it still remains a formidable …
chemodynamic therapy (CDT). Despite devoted efforts, it still remains a formidable …
Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy
Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …
Biomedicine meets nanozyme catalytic chemistry
C Cao, N Yang, X Wang, J Shao, X Song… - Coordination Chemistry …, 2023 - Elsevier
Nanozymes, tiny-sized artificial enzymes, hold promise in mimicking the catalytic actions of
natural enzymes. The intersection between nanozyme and biomedicine has sparked …
natural enzymes. The intersection between nanozyme and biomedicine has sparked …