Extracellular matrix (ECM) molecules that are released by neurons and glial cells form
perineuronal nets (PNNs) and modulate many neuronal and glial functions. PNNs, whose …

Increased mortality and diverse morbidities are globally associated with exposure to
ambient air pollution (AAP), cigarette smoke (CS), and household air pollution (HAP). The …

Lead (Pb), environmentally abundant heavy-metal pollutant, is a strong toxicant for the
developing central nervous system. Pb intoxication in children, even at low doses, is found …

Accumulating evidence suggests that the detrimental effect of nicotine and tobacco smoke
on the central nervous system (CNS) is caused by the neurotoxic role of nicotine on blood …

Cigarette smoking is known to be harmful to health, and is considered the main cause of
death worldwide, especially in India. Among the well-distinguished diseases related to …

Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and currently the 3rd largest cause of death in the world, with approximately 3.23 million …

Nicotine is the major neurotoxicant in cigarettes that affects many transmitter systems within
the brain as well as other factors, including the growth factors. Brain derived neurotrophic …

Abstract Background Lead (Pb), a heavy metal, and quinolinic acid (QA), a metabolite of the
kynurenine pathway of tryptophan metabolism, are known neurotoxicants. Both Pb and QA …

Clinical psychiatric disorders of depression, anxiety, and substance abuse are most
prevalent after traumatic brain injury (TBI). Pre-clinical research has focused on depression …

Lead (Pb) exposure damages synaptic structural plasticity that results in cognitive
impairment. Resveratrol, a natural polyphenolic compound, is one of the most potent …