The natural history of chronic hepatitis B virus (HBV) infection and disease is complex and
highly variable. We review the natural history of chronic hepatitis B with emphasis on the …

Molecular epidemiologic studies reveal remarkable differences in the geographical
distribution of hepatitis B virus (HBV) genotypes. The frequency of mutants among HBV …

Large volume of new data on the natural history and treatment of chronic hepatitis B virus
(HBV) infection have become available since 2008. These include further studies in …

At least 10 hepatitis B virus (HBV) genotypes (A to J) with distinct geographic distributions
and several HBV mutants, including precore/core promoter mutations and pre-S/S deletion …

Large amounts of new data on the natural history and treatment of chronic hepatitis B virus
(HBV) infection have become available since 2005. These include long-term follow-up …

Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

Sequences of 234 complete genomes and 631 hepatitis B surface antigen genes were used
to assess the worldwide diversity of hepatitis B virus (HBV). Apart from the described two …

Worldwide about 350 million people are chronic carriers of the hepatitis B virus (HBV). The
infection can cause acute and chronic liver disease including cirrhosis and hepatocellular …

Outcomes of chronic hepatitis B virus (HBV) infection are heterogeneous. Estimates of
annual incidence of cirrhosis and hepatocellular carcinoma (HCC) are 2–10% and 1–3 …

The clinical course of infections with the hepatitis B virus (HBV) substantially varies between
individuals, as a consequence of a complex interplay between viral, host, environmental and …