Cellular iron homeostasis is maintained by iron regulatory proteins 1 and 2 (IRP1 and IRP2).
IRPs bind to iron-responsive elements (IREs) located in the untranslated regions of mRNAs …

▪ Abstract Complex II is the only membrane-bound component of the Krebs cycle and in
addition functions as a member of the electron transport chain in mitochondria and in many …

Yeast cells contain a family of three monothiol glutaredoxins: Grx3, 4, and 5. Absence of
Grx5 leads to constitutive oxidative damage, exacerbating that caused by external oxidants …

Iron–sulfur (Fe–S) clusters are essential for numerous biological processes, including
mitochondrial respiratory chain activity and various other enzymatic and regulatory …

Abstract Iron–sulfur (Fe–S) clusters are ancient, ubiquitous cofactors composed of iron and
inorganic sulfur. The combination of the chemical reactivity of iron and sulfur, together with …

Iron–sulphur clusters are important cofactors for proteins that are involved in many cellular
processes, including electron transport, enzymatic catalysis and regulation. The enzymes …

Abstract Iron-sulfur (Fe/S) clusters require a complex set of proteins to become assembled
and incorporated into apoproteins in a living cell. Researchers have described three distinct …

Cysteine desulfurase is a pyridoxal 5′-phosphate (PLP)-dependent homodimeric enzyme
that catalyzes the conversion of L-cysteine to L-alanine and sulfane sulfur via the formation …

Iron is an essential element for all eukaryotes. The facile ability of iron to gain and lose
electrons permits its participation in a wide variety of oxidation-reduction reactions. Further …

Iron–sulfur (Fe–S) clusters (ISCs) are versatile, ancient co-factors of proteins that are
involved in electron transport, enzyme catalysis and regulation of gene expression. The …