Extracellular vesicles: a rising star for therapeutics and drug delivery

S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …

Future of digital assays to resolve clinical heterogeneity of single extracellular vesicles

RTT Morales, J Ko - ACS nano, 2022 - ACS Publications
Extracellular vesicles (EVs) are complex lipid membrane vehicles with variable expressions
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …

[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine

M Li, F Fang, M Sun, Y Zhang, M Hu, J Zhang - Theranostics, 2022 - ncbi.nlm.nih.gov
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …

3D‐Printed Functional Hydrogel by DNA‐Induced Biomineralization for Accelerated Diabetic Wound Healing

N Kim, H Lee, G Han, M Kang, S Park… - Advanced …, 2023 - Wiley Online Library
Chronic wounds in diabetic patients are challenging because their prolonged inflammation
makes healing difficult, thus burdening patients, society, and health care systems …

Recent advances in extracellular vesicle engineering and its applications to regenerative medicine

WK Rhim, JY Kim, SY Lee, SG Cha, JM Park… - Biomaterials …, 2023 - spj.science.org
Extracellular vesicles (EVs) are nanosized particles that are released from cells and reflect
the characteristics of the mother cell. Recently, the EVs have been used in several types of …

A versatile hydrogel with antibacterial and sequential drug-releasing capability for the programmable healing of infectious keratitis

S Meng, H Hu, Y Qiao, F Wang, BN Zhang, D Sun… - ACS …, 2023 - ACS Publications
Hydrogels have attracted tremendous attention as favorable corneal substitutes for treating
severe infectious keratitis (IK). However, current hydrogel-based corneal substitutes were …

Bolstering the secretion and bioactivities of umbilical cord MSC-derived extracellular vesicles with 3D culture and priming in chemically defined media

JY Kim, WK Rhim, SG Cha, J Woo, JY Lee, CG Park… - Nano …, 2022 - Springer
Human mesenchymal stem cells (hMSCs)-derived extracellular vesicles (EVs) have been
known to possess the features of the origin cell with nano size and have shown therapeutic …

[HTML][HTML] Extracellular vesicles for renal therapeutics: State of the art and future perspective

TT Tang, B Wang, LL Lv, Z Dong, BC Liu - Journal of Controlled Release, 2022 - Elsevier
With the ever-increasing burden of kidney disease, the need for developing new
therapeutics to manage this disease has never been greater. Extracellular vesicles (EVs) …

Decellularized extracellular matrix-based composite scaffolds for tissue engineering and regenerative medicine

P Xu, RK Kankala, S Wang… - Regenerative Biomaterials, 2024 - academic.oup.com
Despite the considerable advancements in fabricating polymeric-based scaffolds for tissue
engineering, the clinical transformation of these scaffolds remained a big challenge because …

Multimodal therapy strategy based on a bioactive hydrogel for repair of spinal cord injury

EJ Roh, DS Kim, JH Kim, CS Lim, H Choi, SY Kwon… - Biomaterials, 2023 - Elsevier
Traumatic spinal cord injury results in permanent and serious neurological impairment, but
there is no effective treatment yet. Tissue engineering approaches offer great potential for …