Bacterial antibiotic resistance: the most critical pathogens

G Mancuso, A Midiri, E Gerace, C Biondo - Pathogens, 2021 - mdpi.com
Antibiotics have made it possible to treat bacterial infections such as meningitis and
bacteraemia that, prior to their introduction, were untreatable and consequently fatal …

Methicillin-resistant Staphylococcus aureus

AS Lee, H De Lencastre, J Garau… - Nature reviews Disease …, 2018 - nature.com
Since the 1960s, methicillin-resistant Staphylococcus aureus (MRSA) has emerged,
disseminated globally and become a leading cause of bacterial infections in both health …

[HTML][HTML] Burden of bacterial bloodstream infection—a brief update on epidemiology and significance of multidrug-resistant pathogens

WV Kern, S Rieg - Clinical Microbiology and Infection, 2020 - Elsevier
Background Bloodstream infections comprise a wide variety of pathogens and clinical
syndromes with considerable overlap with similar syndromes of non-bacteraemic infections …

Combination of Vancomycin and β-Lactam Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: A Pilot Multicenter Randomized Controlled Trial

JS Davis, A Sud, MVN O'Sullivan… - Clinical Infectious …, 2016 - academic.oup.com
Background. In vitro laboratory and animal studies demonstrate a synergistic role for the
combination of vancomycin and antistaphylococcal β-lactams for methicillin-resistant …

Efficient elimination of multidrug-resistant bacteria using copper sulfide nanozymes anchored to graphene oxide nanosheets

W Wang, B Li, H Yang, Z Lin, L Chen, Z Li, J Ge… - Nano Research, 2020 - Springer
Antibacterial nanomaterials have attracted growing interest for bacterial infection therapy.
However, most nanomaterials eliminate bacteria either physically or chemically, which …

Daptomycin versus Vancomycin for the Treatment of Methicillin-Resistant Staphylococcus aureus Bloodstream Infection with or without Endocarditis: A Systematic …

AE Maraolo, A Giaccone, I Gentile, A Saracino… - Antibiotics, 2021 - mdpi.com
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of
invasive infections, mainly bloodstream infections (BSI) with or without endocarditis. The …

Longitudinal genomic surveillance of MRSA in the UK reveals transmission patterns in hospitals and the community

F Coll, EM Harrison, MS Toleman, S Reuter… - Science translational …, 2017 - science.org
Genome sequencing has provided snapshots of the transmission of methicillin-resistant
Staphylococcus aureus (MRSA) during suspected outbreaks in isolated hospital wards …

Methicillin-susceptible and Methicillin-resistant Staphylococcus aureus Bacteremia: Nationwide Estimates of 30-Day Readmission, In-hospital Mortality, Length of …

K Inagaki, J Lucar, C Blackshear… - Clinical Infectious …, 2019 - academic.oup.com
Background Information on outcomes of methicillin-susceptible and-resistant
Staphylococcus aureus (MSSA and MRSA, respectively) bacteremia, particularly …

Evidence for a causal link between sepsis and long-term mortality: a systematic review of epidemiologic studies

M Shankar-Hari, M Ambler, V Mahalingasivam… - Critical Care, 2016 - Springer
Background In addition to acute hospital mortality, sepsis is associated with higher risk of
death following hospital discharge. We assessed the strength of epidemiological evidence …

Burden of invasive Staphylococcus aureus infections in hospitalized infants

JE Ericson, VO Popoola, PB Smith, DK Benjamin… - JAMA …, 2015 - jamanetwork.com
Importance Staphylococcus aureusis a frequent cause of infection in hospitalized infants.
These infections are associated with increased mortality and morbidity and longer hospital …