Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …

Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

The identification of high-risk human papillomavirus (HPV) types as a necessary cause of
cervical cancer offers the prospect of effective primary prevention and the possibility of …

The retinoblastoma (RB) tumour suppressor gene is functionally inactivated in a broad
range of paediatric and adult cancers, and a plethora of cellular functions and partners have …

The roles of Oct4 and Nanog in maintaining self-renewal and undifferentiated status of adult
stem cells are unclear. Here, increase in Oct4 and Nanog expression along with increased …

Decades of research on the human papillomavirus oncogenes, E6 and E7, have given us
huge amounts of data on their expression, functions and structures. We know much about …

Background & Aims Many genetic and environmental factors, including family history, dietary
fat, and inflammation, increase risk for colon cancer development. Peroxisome proliferator …

Dicer initiates RNA interference by generating small RNAs involved in various silencing
pathways. Dicer participates in centromeric silencing, but its role in the epigenetic regulation …

Cervical cancer is the fourth most frequent cancer in women worldwide and a major cause of
mortality in developing countries. Persistent infection with high-risk human papillomavirus …

Arsenic ranks as the number one toxic environmental contaminant. In humans, arsenic
exposure is associated with various forms of cancer, cardiovascular and skin diseases …