Biomechanics of chondrocytes and chondrons in healthy conditions and osteoarthritis: a review of the mechanical characterisations at the microscale

S Pettenuzzo, A Arduino, E Belluzzi, A Pozzuoli… - Biomedicines, 2023 - mdpi.com
Biomechanical studies are expanding across a variety of fields, from biomedicine to
biomedical engineering. From the molecular to the system level, mechanical stimuli are …

Biomechanical properties and mechanobiology of the articular chondrocyte

C Chen, DT Tambe, L Deng… - American Journal of …, 2013 - journals.physiology.org
To withstand physiological loading over a lifetime, human synovial joints are covered and
protected by articular cartilage, a layer of low-friction, load-bearing tissue. The unique …

Clutchable series-elastic actuator: Implications for prosthetic knee design

EJ Rouse, LM Mooney, HM Herr - The International Journal …, 2014 - journals.sagepub.com
Currently, the mobility of above-knee amputees is limited by the lack of available prostheses
that can efficiently replicate biologically accurate movements. In this study, a powered knee …

Mechanisms of gait asymmetry due to push-off deficiency in unilateral amputees

PG Adamczyk, AD Kuo - IEEE transactions on neural systems …, 2014 - ieeexplore.ieee.org
Unilateral lower-limb amputees exhibit asymmetry in many gait features, such as ground
force, step time, step length, and joint mechanics. Although these asymmetries result from …

Effects of a powered ankle-foot prosthesis on kinetic loading of the unaffected leg during level-ground walking

AM Grabowski, S D'Andrea - Journal of neuroengineering and …, 2013 - Springer
Background People with a lower-extremity amputation that use conventional passive-elastic
ankle-foot prostheses encounter a series of stress-related challenges during walking such …

Sagittal plane gait characteristics in hip osteoarthritis patients with mild to moderate symptoms compared to healthy controls: a cross-sectional study

I Eitzen, L Fernandes, L Nordsletten… - BMC musculoskeletal …, 2012 - Springer
Background Existent biomechanical studies on hip osteoarthritic gait have primarily focused
on the end stage of disease. Consequently, there is no clear consensus on which specific …

Unilateral transfemoral osseointegrated prostheses improve joint loading during walking

NW Vandenberg, JW Stoneback, H Davis-Wilson… - Journal of …, 2023 - Elsevier
People with unilateral transfemoral amputation using socket prostheses are at increased risk
for developing osteoarthritis in both the residual hip and intact lower-limb joints …

Asymmetrical movements of the lumbopelvic region: is this a potential mechanism for low back pain in people with lower limb amputation?

H Devan, P Hendrick, DC Ribeiro, LA Hale… - Medical hypotheses, 2014 - Elsevier
Low back pain (LBP) is a major secondary disabling condition following lower limb
amputation including persons with above-knee and below-knee amputation. Whilst the …

A non-invasive wearable sensory leg neuroprosthesis: mechanical, electrical and functional validation

C Basla, L Chee, G Valle… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. Lower limb amputees suffer from a variety of functional deficits related to the
absence of sensory communication between the central nervous system and the lost …

Increasing prosthetic foot energy return affects whole-body mechanics during walking on level ground and slopes

WL Childers, KZ Takahashi - Scientific reports, 2018 - nature.com
Prosthetic feet are designed to store energy during early stance and then release a portion
of that energy during late stance. The usefulness of providing more energy return depends …