Controlled slow-release drug-eluting stents for the prevention of coronary restenosis: recent progress and future prospects

T Hu, J Yang, K Cui, Q Rao, T Yin, L Tan… - … applied materials & …, 2015 - ACS Publications
Drug-eluting stents (DES) have become more widely used by cardiologists than bare metal
stents (BMS) because of their better ability to control restenosis. However, recognized …

State of the art: coronary artery stents-past, present and future

GG Stefanini, RA Byrne, S Windecker… - …, 2017 - eurointervention.pcronline.com
The first percutaneous coronary intervention (PCI) was performed in September 1977 by
Andreas Grüntzig using a rudimentary balloon angioplasty catheter mounted on a fixed wire …

A bioresorbable everolimus-eluting scaffold versus a metallic everolimus-eluting stent for ischaemic heart disease caused by de-novo native coronary artery lesions …

PW Serruys, B Chevalier, D Dudek, A Cequier… - The Lancet, 2015 - thelancet.com
Background Despite rapid dissemination of an everolimus-eluting bioresorbable scaffold for
treatment for coronary artery disease, no data from comparisons with its metallic stent …

An overview of in vitro drug release methods for drug-eluting stents

N Abbasnezhad, N Zirak, S Champmartin… - Polymers, 2022 - mdpi.com
The drug release profile of drug-eluting stents (DESs) is affected by a number of factors,
including the formulation, design, and physicochemical properties of the utilized material …

Coronary stents: the impact of technological advances on clinical outcomes

MG Mennuni, PA Pagnotta, GG Stefanini - Annals of biomedical …, 2016 - Springer
Percutaneous coronary interventions (PCI) were proposed in the late 1970s as an
alternative to surgical coronary artery bypass grafting for the treatment of coronary artery …

The impact of blood rheology on drug transport in stented arteries: steady simulations

PRS Vijayaratnam, CC O'Brien, JA Reizes, TJ Barber… - PloS one, 2015 - journals.plos.org
Background and Methods It is important to ensure that blood flow is modelled accurately in
numerical studies of arteries featuring drug-eluting stents due to the significant proportion of …

Modelling the impact of atherosclerosis on drug release and distribution from coronary stents

CM McKittrick, S Kennedy, KG Oldroyd… - Annals of biomedical …, 2016 - Springer
Although drug-eluting stents (DES) are now widely used for the treatment of coronary heart
disease, there remains considerable scope for the development of enhanced designs which …

Drug deposition in coronary arteries with overlapping drug-eluting stents

F Rikhtegar, ER Edelman, U Olgac… - Journal of Controlled …, 2016 - Elsevier
Drug-eluting stents are accepted as mainstream endovascular therapy, yet concerns for their
safety may be under-appreciated. While failure from restenosis has dropped to below 5 …

How does stent expansion alter drug transport properties of the arterial wall?

J Escuer, M Cebollero, E Pena, S McGinty… - Journal of the …, 2020 - Elsevier
Stents have become the most successful device to treat advanced atherosclerotic lesions.
However, one of the main issues with these interventions is the development of restenosis …

[HTML][HTML] Modelling drug release from polymer-free coronary stents with microporous surfaces

TTN Vo, S Morgan, C McCormick, S McGinty… - International journal of …, 2018 - Elsevier
Traditional coronary drug-eluting stents (DES) are made from metal and are coated with a
permanent polymer film containing an anti-proliferative drug. Subsequent to stent …