The ability to monitor response to therapy for tuberculosis (TB) and confirm adequate
treatment would be a major advance. The low reversion rate of interferon-gamma based …

Tuberculosis (TB) is still a global health concern, especially in resource-poor countries such
as The Gambia. Defining protective immunity to TB is challenging: its pathogenesis is …

Multiple cytokines and inflammatory markers control TB infection. We aimed to investigate
the changes in multiple cytokines and inflammatory markers in active TB patients following …

Mono-and multifunctional specific CD4+ and CD8+ T-cell responses were evaluated to
improve the immune-based detection of active tuberculosis (TB) and latent infection (LTBI) …

The number of studies which evaluated interferon-gamma release assays (IGRAs) results
after anti-tuberculosis (TB) treatment has been rapidly increasing. The aim of this study was …

The early control and prevention of cancer contributes effectively interventions and cancer
therapies. Secretory protein, one of the richest biomarkers, is proved important as molecular …

Background The interferon‐γ (IFN‐γ) release assay (IGRA) is widely used to diagnose
tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb). However, indeterminate …

Objectives A biomarker indicating successful tuberculosis (TB) therapy would assist in
determining appropriate length of treatment. This study aimed to determine changes in …

Background Identifying latent tuberculosis infection (LTBI) in people migrating from TB
endemic regions to low incidence countries is an important control measure. However, no …

In an effort to develop more effective therapy for tuberculosis (TB), research efforts are
looking toward host-directed therapy, reprograming the body's natural defenses to better …