Antimicrobial host defence peptides: functions and clinical potential

N Mookherjee, MA Anderson, HP Haagsman… - Nature reviews Drug …, 2020 - nature.com
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo

P Kumar, JN Kizhakkedathu, SK Straus - Biomolecules, 2018 - mdpi.com
Antibiotic resistance is projected as one of the greatest threats to human health in the future
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …

Dietary polyphenol impact on gut health and microbiota

MLY Wan, VA Co, H El-Nezami - Critical reviews in food science …, 2021 - Taylor & Francis
Polyphenols are naturally occurring compounds in plants and they are the most abundant
antioxidants in the human diet. Due to their considerable structural diversity, this largely …

Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria

JM Ageitos, A Sánchez-Pérez, P Calo-Mata… - Biochemical …, 2017 - Elsevier
Antimicrobial peptides (AMPs) are short peptidic molecules produced by most living
creatures. They help unicellular organisms to successfully compete for nutrients with other …

Antimicrobial peptides: mechanism of action, activity and clinical potential

QY Zhang, ZB Yan, YM Meng, XY Hong, G Shao… - Military Medical …, 2021 - Springer
The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

The therapeutic applications of antimicrobial peptides (AMPs): a patent review

HK Kang, C Kim, CH Seo, Y Park - Journal of microbiology, 2017 - Springer
Antimicrobial peptides (AMPs) are small molecules with a broad spectrum of antibiotic
activities against bacteria, yeasts, fungi, and viruses and cytotoxic activity on cancer cells, in …

Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era

M Kostakioti, M Hadjifrangiskou… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Biofilm formation constitutes an alternative lifestyle in which microorganisms adopt a
multicellular behavior that facilitates and/or prolongs survival in diverse environmental …

Defensins: The natural peptide antibiotic

X Gao, J Ding, C Liao, J Xu, X Liu, W Lu - Advanced drug delivery reviews, 2021 - Elsevier
Defensins are a family of cationic antimicrobial peptides active against a broad range of
infectious microbes including bacteria, viruses and fungi, playing important roles as innate …

[HTML][HTML] Antimicrobial peptides as potential anti-biofilm agents against multidrug-resistant bacteria

PY Chung, R Khanum - Journal of microbiology, immunology and infection, 2017 - Elsevier
Bacterial resistance to commonly used drugs has become a global health problem, causing
increased infection cases and mortality rate. One of the main virulence determinants in many …

Epithelial antimicrobial defence of the skin and intestine

RL Gallo, LV Hooper - Nature Reviews Immunology, 2012 - nature.com
Surface tissues of the body such as the skin and intestinal tract are in direct contact with the
external environment and are thus continuously exposed to large numbers of …