Inhibition of Poly (ADP-ribose) polymerase impairs Epstein Barr Virus lytic cycle progression

S Mattiussi, I Tempera, G Matusali, G Mearini… - Infectious agents and …, 2007 - Springer
Background Poly (ADP-ribosylation) is a post-translational modification of nuclear proteins
involved in several cellular events as well as in processes that characterize the infective …

Structure‐Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits

E Maurits, CG Degeling, AF Kisselev, BI Florea… - …, 2020 - Wiley Online Library
Proteasomes are established therapeutic targets for hematological cancers and promising
targets for autoimmune diseases. In the past, we have designed and synthesized …

Epstein-Barr virus lytic cycle activation alters proteasome subunit expression in Burkitt's lymphoma cells

A De Leo, G Matusali, G Arena, L Di Renzo, E Mattia - 2010 - degruyter.com
We have shown that Epstein-Barr virus (EBV) lytic cycle activation in Burkitt's lymphoma (BL)
cells down-regulates chymotrypsin-and caspase-like activities of the proteasome. The aim of …

[PDF][PDF] Targeting human proteasomes: Substrates, inhibitors and prodrugs

E Maurits - 2020 - scholarlypublications …
The ubiquitin-proteasome system (UPS) plays an essential role in the degradation of
proteins involved in a variety of cellular processes, including, but not limited to …