Hepatic fibrosis: It is time to go with hepatic stellate cell-specific therapeutic targets
Hepatic fibrosis is a pathological lesion, characterized by the progressive accumulation of
extracellular matrix (ECM) in the perisinusoidal space and it is a major problem in chronic …
extracellular matrix (ECM) in the perisinusoidal space and it is a major problem in chronic …
Phytobioactive compounds as therapeutic agents for human diseases: A review
Phytobioactive compounds are plant secondary metabolites and bioactive compounds
abundantly present in medicinal plants and have remarkable therapeutic potential. Oxidative …
abundantly present in medicinal plants and have remarkable therapeutic potential. Oxidative …
The potential and action mechanism of polyphenols in the treatment of liver diseases
S Li, HY Tan, N Wang, F Cheung… - … medicine and cellular …, 2018 - Wiley Online Library
Liver disease, involving a wide range of liver pathologies from fatty liver, hepatitis, and
fibrosis to cirrhosis and hepatocellular carcinoma, is a serious health problem worldwide. In …
fibrosis to cirrhosis and hepatocellular carcinoma, is a serious health problem worldwide. In …
[HTML][HTML] Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells
Y Jia, F Wang, Q Guo, M Li, L Wang, Z Zhang, S Jiang… - Redox biology, 2018 - Elsevier
It is generally recognized that hepatic fibrogenesis is an end result of increased extracellular
matrix (ECM) production from the activation and proliferation of hepatic stellate cells (HSCs) …
matrix (ECM) production from the activation and proliferation of hepatic stellate cells (HSCs) …
Cell death in hepatocellular carcinoma: pathogenesis and therapeutic opportunities
E García-Pras, A Fernández-Iglesias, J Gracia-Sancho… - Cancers, 2021 - mdpi.com
Simple Summary The progression of liver tumors is highly influenced by the interactions
between cancer cells and the surrounding environment, and, consequently, can determine …
between cancer cells and the surrounding environment, and, consequently, can determine …
Gallic acid has anticancer activity and enhances the anticancer effects of cisplatin in non‑small cell lung cancer A549 cells via the JAK/STAT3 signaling pathway
T Zhang, L Ma, P Wu, W Li, T Li, R Gu… - Oncology …, 2019 - spandidos-publications.com
Abstract Gallic acid (3, 4, 5‑trihydroxybenzoic acid; GA), a plant‑derived natural phenolic
compound, has been reported to prevent the development and progression of various types …
compound, has been reported to prevent the development and progression of various types …
[HTML][HTML] Yinchenhao decoction suppresses rat liver fibrosis involved in an apoptosis regulation mechanism based on network pharmacology and transcriptomic …
FF Cai, YQ Bian, R Wu, Y Sun, XL Chen… - Biomedicine & …, 2019 - Elsevier
Yinchenhao decoction (YCHD) is a classical Traditional Chinese Medicine (TCM) formula
that has been widely used in the treatment of liver fibrosis caused by chronic hepatitis B and …
that has been widely used in the treatment of liver fibrosis caused by chronic hepatitis B and …
A review of the phytochemical, pharmacological, pharmacokinetic, and toxicological evaluation of Quercus Infectoria galls
A Elham, M Arken, G Kalimanjan, A Arkin… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Quercus Infectoria galls (QIG) have a long history
of use in traditional Chinese medicine and traditional Uyghur medicine for the treatment of …
of use in traditional Chinese medicine and traditional Uyghur medicine for the treatment of …
Human diet‐derived polyphenolic compounds and hepatic diseases: From therapeutic mechanisms to clinical utilization
Q Hu, W Zhang, F Wei, M Huang, M Shu… - Phytotherapy …, 2024 - Wiley Online Library
This review focuses on the potential ameliorative effects of polyphenolic compounds derived
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …
Roles of necroptosis in alcoholic liver disease and hepatic pathogenesis
Y Zhou, R Wu, X Wang, X Bao, C Lu - Cell Proliferation, 2022 - Wiley Online Library
Chronic alcohol consumption can cause alcoholic liver disease (ALD), leading to morbidity
and mortality worldwide. Complex disease progression of ALD varies from alcoholic fatty …
and mortality worldwide. Complex disease progression of ALD varies from alcoholic fatty …