Re-evaluation of the WHO (2010) formaldehyde indoor air quality guideline for cancer risk assessment

GD Nielsen, ST Larsen, P Wolkoff - Archives of toxicology, 2017 - Springer
Abstract In 2010, the World Health Organization (WHO) established an indoor air quality
guideline for short-and long-term exposures to formaldehyde (FA) of 0.1 mg/m 3 (0.08 ppm) …

Micronuclei frequency in peripheral blood lymphocytes and cancer risk: evidence from human studies

S Bonassi, R El-Zein, C Bolognesi, M Fenech - Mutagenesis, 2011 - academic.oup.com
Over a century ago, Theodor Boveri paved the way to mechanistic studies linking
chromosomal abnormalities to cancer pathogenesis. Since then, theoretical and empirical …

[图书][B] Casarett and Doull's toxicology: the basic science of poisons

CD Klaassen, MO Amdur - 2013 - researchgate.net
The question of what constitutes an acceptable risk is a matter of judgement. Such decisions
are multifaceted and complex, and involve a balance of risk and benefit. High risks may be …

Heavy ion carcinogenesis and human space exploration

M Durante, FA Cucinotta - Nature Reviews Cancer, 2008 - nature.com
Before the human exploration of Mars or long-duration missions on the Earth's moon, the
risk of cancer and other diseases from space radiation must be accurately estimated and …

Risks Associated with Low Doses and Low Dose Rates of Ionizing Radiation: Why Linearity May Be (Almost) the Best We Can Do1

MP Little, R Wakeford, EJ Tawn, SD Bouffler… - Radiology, 2009 - pubs.rsna.org
Deterministic and stochastic effects associated with high-dose ionizing radiation (x-ray)
exposure have been known for almost as long as ionizing radiation itself (1–3). At lower …

What is the best biomarker to assess arsenic exposure via drinking water?

N Marchiset-Ferlay, C Savanovitch… - Environment …, 2012 - Elsevier
Arsenic (As) is a ubiquitous element. The current WHO guideline for As in drinking water is
10μg/L. Furthermore, about 130 million people have only access to drinking water …

Models of carcinogenesis: an overview

P Vineis, A Schatzkin, JD Potter - Carcinogenesis, 2010 - academic.oup.com
At least five coherent models of carcinogenesis have been proposed in the history of cancer
research in the last century. Model 1 is mainly centered around mutations, and its main focus …

Genetic polymorphisms and micronucleus formation: a review of the literature

G Iarmarcovai, S Bonassi, A Botta, RA Baan… - … Research/Reviews in …, 2008 - Elsevier
The formation of micronuclei (MN) is extensively used in molecular epidemiology as a
biomarker of chromosomal damage, genome instability, and eventually of cancer risk. The …

A systematic comparison of the actual, potential, and theoretical health effects of cobalt and chromium exposures from industry and surgical implants

GM Keegan, ID Learmonth, C Case - Critical reviews in toxicology, 2008 - Taylor & Francis
Humans are exposed to cobalt (Co) and chromium (Cr) from industry and surgical devices,
most notably orthopedic joint replacements. This review compares the potential health …

Role of oxidative stress in preeclampsia and intrauterine growth restriction

I Mert, A Sargın Oruc, S Yuksel… - Journal of Obstetrics …, 2012 - Wiley Online Library
Aim: The aim of the present study was to evaluate the role of oxidative stress and DNA
damage in preeclampsia and intrauterine growth restriction (IUGR). Material and Methods …