The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?

EO Lillie, B Patay, J Diamant, B Issell… - Personalized …, 2011 - Taylor & Francis
N-of-1 or single subject clinical trials consider an individual patient as the sole unit of
observation in a study investigating the efficacy or side-effect profiles of different …

Chronic kidney disease: a clinical model of premature aging

P Stenvinkel, TE Larsson - American journal of kidney diseases, 2013 - Elsevier
Premature aging is a process associated with a progressive accumulation of deleterious
changes over time, an impairment of physiologic functions, and an increase in the risk of …

Эндотелиальная дисфункция и ее основные маркеры

ЛВ Васина, НН Петрищев, ТД Власов - Регионарное …, 2017 - microcirc.ru
Аннотация В настоящее время дисфункция эндотелия рассматривается как
универсальное неспецифическое звено в патогенезе многих заболеваний, в первую …

The vasculopathy of juvenile dermatomyositis

C Papadopoulou, LJ McCann - Frontiers in pediatrics, 2018 - frontiersin.org
Juvenile dermatomyositis (JDM) is a rare autoimmune disease mainly characterized by
muscle and skin involvement. Vasculopathy is considered central to the pathogenesis of the …

Методы диагностики эндотелиальной дисфункции

АН Иванов, АА Гречихин, ИА Норкин… - Регионарное …, 2014 - microcirc.ru
Аннотация Эндотелиальная дисфункция определяется как патологическое состояние,
характеризующееся прогрессирующим повреждением клеток эндотелия и …

[HTML][HTML] Metabolic theory of septic shock

J Pravda - World journal of critical care medicine, 2014 - ncbi.nlm.nih.gov
Septic shock is a life threatening condition that can develop subsequent to infection.
Mortality can reach as high as 80% with over 150000 deaths yearly in the United States …

Markers of endothelial dysfunction

LV Vasina, NN Petrishchev, TD Vlasov - Regional blood circulation and …, 2017 - microcirc.ru
Endothelial dysfunction is considered as a universal non-specific link in the pathogenesis of
many diseases, primarily the cardiovascular system. This review is devoted to the discussion …

Update on biomarkers of vasculopathy in juvenile and adult myositis

K McLellan, C Papadopoulou - Current Rheumatology Reports, 2022 - Springer
Abstract Purpose of Review Although rare, idiopathic inflammatory myopathies (IIM)
comprise a heterogeneous group of autoimmune conditions in adults and children …

Increased numbers of small circulating endothelial cells in renal cell cancer patients treated with sunitinib

L Vroling, AAM van der Veldt, RR de Haas… - Angiogenesis, 2009 - Springer
Mature circulating endothelial cell (CEC) as well as endothelial progenitor populations may
reflect the activity of anti-angiogenic agents on tumor neovasculature or even constitute a …

Low‐dose metronomic chemotherapy with cisplatin: can it suppress angiogenesis in H22 hepatocarcinoma cells?

FZ Shen, J Wang, J Liang, K Mu… - International journal …, 2010 - Wiley Online Library
Low‐dose chemotherapy drugs can suppress tumours by restraining tumour vessel growth
and preventing the repair of damaged vascular endothelial cells. Cisplatin is a broad …