Variants of core histones and their roles in cell fate decisions, development and cancer
M Buschbeck, SB Hake - Nature reviews Molecular cell biology, 2017 - nature.com
Histone variants endow chromatin with unique properties and show a specific genomic
distribution that is regulated by specific deposition and removal machineries. These variants …
distribution that is regulated by specific deposition and removal machineries. These variants …
[HTML][HTML] Epigenetic regulation of the histone-to-protamine transition during spermiogenesis
J Bao, MT Bedford - Reproduction (Cambridge, England), 2016 - ncbi.nlm.nih.gov
In mammals, male germ cells differentiate from haploid round spermatids to flagella-
containing motile sperm, in a process called spermiogenesis. This process is distinct from …
containing motile sperm, in a process called spermiogenesis. This process is distinct from …
[HTML][HTML] Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
We report the identification of 67 previously undescribed histone modifications, increasing
the current number of known histone marks by about 70%. We further investigated one of the …
the current number of known histone marks by about 70%. We further investigated one of the …
ATP-dependent chromatin remodeling during mammalian development
SK Hota, BG Bruneau - Development, 2016 - journals.biologists.com
Precise gene expression ensures proper stem and progenitor cell differentiation, lineage
commitment and organogenesis during mammalian development. ATP-dependent …
commitment and organogenesis during mammalian development. ATP-dependent …
[HTML][HTML] Essential role of histone replacement and modifications in male fertility
Spermiogenesis is a complex cellular differentiation process that the germ cells undergo a
distinct morphological change, and the protamines replace the core histones to facilitate …
distinct morphological change, and the protamines replace the core histones to facilitate …
Protamines and male infertility
R Oliva - Human reproduction update, 2006 - academic.oup.com
Protamines are the major nuclear sperm proteins. The human sperm nucleus contains two
types of protamine: protamine 1 (P1) encoded by a single-copy gene and the family of …
types of protamine: protamine 1 (P1) encoded by a single-copy gene and the family of …
[HTML][HTML] A decade of exploring the mammalian sperm epigenome: paternal epigenetic and transgenerational inheritance
A Champroux, J Cocquet, J Henry-Berger… - Frontiers in Cell and …, 2018 - frontiersin.org
The past decade has seen a tremendous increase in interest and progress in the field of
sperm epigenetics. Studies have shown that chromatin regulation during male germline …
sperm epigenetics. Studies have shown that chromatin regulation during male germline …
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain
J Moriniere, S Rousseaux, U Steuerwald… - Nature, 2009 - nature.com
A key step in many chromatin-related processes is the recognition of histone post-
translational modifications by effector modules such as bromodomains and chromo-like …
translational modifications by effector modules such as bromodomains and chromo-like …
Covalent modifications of histones during development and disease pathogenesis
SR Bhaumik, E Smith, A Shilatifard - Nature structural & molecular …, 2007 - nature.com
Covalent modifications of histones are central to the regulation of chromatin dynamics, and,
therefore, many biological processes involving chromatin, such as replication, repair …
therefore, many biological processes involving chromatin, such as replication, repair …
[HTML][HTML] Abnormal histone replacement following BPA exposure affects spermatogenesis and fertility sequentially
DY Ryu, WK Pang, EO Adegoke, MS Rahman… - Environment …, 2022 - Elsevier
Bisphenol A (BPA) is an endocrine-disrupting chemical widely distributed in the
environment. Its exposure has been linked to male infertility in animals and humans due to …
environment. Its exposure has been linked to male infertility in animals and humans due to …