Gene transcription and cell metabolism are two fundamental biological processes that
mutually regulate each other. Upregulated or altered expression of glucose metabolic genes …

Molecular recognition between proteins and their interacting partners underlies the
biochemistry of living organisms. Specificity in this recognition is thought to be essential …

Enolase is a glycolytic enzyme, which catalyzes the inter-conversion of 2-phosphoglycerate
to phosphoenolpyruvate. Altered expression of this enzyme is frequently observed in cancer …

Exosomes are 30–100-nm membrane vesicles of endocytic origin that are released after the
fusion of multivesicular bodies (MVBs) with the plasma membrane. While initial studies …

Moonlighting–the performance of more than one function by a single protein–is becoming
recognized as a common phenomenon with important implications for systems biology and …

Studies of the Plasmodium falciparum transcriptome have shown that the tightly controlled
progression of the parasite through the intra-erythrocytic developmental cycle (IDC) is …

Plasmodium species produce an ortholog of the cytokine macrophage migration inhibitory
factor, PMIF, which modulates the host inflammatory response to malaria. Using a novel …

Pathogens have developed particular strategies to infect and invade their hosts. Amongst
these strategies' figures the modulation of several components of the innate immune system …

In unicellular and multicellular eukaryotes, fast cell motility and rapid movement of material
over cell surfaces are often mediated by ciliary or flagellar beating. The conserved defining …

We report the proteomes of four life‐cycle stages of the Apicomplexan parasite Eimeria
tenella. A total of 1868 proteins were identified, with 630, 699, 845 and 1532 found in early …