Transposable elements in cancer

KH Burns - Nature Reviews Cancer, 2017 - nature.com
Transposable elements give rise to interspersed repeats, sequences that comprise most of
our genomes. These mobile DNAs have been historically underappreciated—both because …

Bacterial insertion sequences: their genomic impact and diversity

P Siguier, E Gourbeyre… - FEMS microbiology …, 2014 - academic.oup.com
Insertion sequences (ISs), arguably the smallest and most numerous autonomous
transposable elements (TEs), are important players in shaping their host genomes. This …

Transposable elements and the evolution of regulatory networks

C Feschotte - Nature Reviews Genetics, 2008 - nature.com
The control and coordination of eukaryotic gene expression rely on transcriptional and post-
transcriptional regulatory networks. Although progress has been made in mapping the …

DNA transposons: nature and applications in genomics

M Muñoz-López, JL García-Pérez - Current genomics, 2010 - ingentaconnect.com
Repeated DNA makes up a large fraction of a typical mammalian genome, and some
repetitive elements are able to move within the genome (transposons and retrotransposons) …

DNA transposons and the evolution of eukaryotic genomes

C Feschotte, EJ Pritham - Annu. Rev. Genet., 2007 - annualreviews.org
Transposable elements are mobile genetic units that exhibit broad diversity in their structure
and transposition mechanisms. Transposable elements occupy a large fraction of many …

The impact of transposable elements on eukaryotic genomes: from genome size increase to genetic adaptation to stressful environments

B Chénais, A Caruso, S Hiard, N Casse - Gene, 2012 - Elsevier
Transposable elements (TEs) are present in roughly all genomes. These mobile DNA
sequences are able to invade genomes and their impact on genome evolution is substantial …

Evolutionary implications of horizontal gene transfer

M Syvanen - Annual review of genetics, 2012 - annualreviews.org
The flow of genes between different species represents a form of genetic variation whose
implications have not been fully appreciated. Here I examine some key findings on the …

DNA transposition at work

AB Hickman, F Dyda - Chemical reviews, 2016 - ACS Publications
DNA transposons are defined segments of DNA that are able to move from one genomic
location to another. Movement is facilitated by one or more proteins, called the transposase …

Evolution of pogo, a separate superfamily of IS630-Tc1-mariner transposons, revealing recurrent domestication events in vertebrates

B Gao, Y Wang, M Diaby, W Zong, D Shen, S Wang… - Mobile DNA, 2020 - Springer
Abstracts Background Tc1/mariner and Zator, as two superfamilies of IS630-Tc1-mariner
(ITm) group, have been well-defined. However, the molecular evolution and domestication …

Integrating prokaryotes and eukaryotes: DNA transposases in light of structure

AB Hickman, M Chandler, F Dyda - Critical reviews in biochemistry …, 2010 - Taylor & Francis
DNA rearrangements are important in genome function and evolution. Genetic material can
be rearranged inadvertently during processes such as DNA repair, or can be moved in a …