Neurotrophins (NTs) belong to a family of trophic factors that regulate the survival, growth
and programmed cell death of neurons. In mammals, there are four structurally and …

Immune and glial cells play a pivotal role in chronic pain. Therefore, it is possible that the
pharmacological modulation of neurotransmission from an exclusively neuronal perspective …

Multiple Sclerosis (MS) is an inflammatory demyelinating disorder of central nervous system
(CNS). Polyphenol curcumin has been used in traditional medicine as an effective drug for a …

The interactions between a prior program of regular exercise and the development of
experimental autoimmune encephalomyelitis (EAE)-mediated responses were evaluated. In …

The central nervous system (CNS) regulates and coordinates an extensive array of complex
processes requiring harmonious regulation of specific genes. CNS disorders represent a …

Multiple sclerosis (MS) is a multifaceted, complex and chronic neurological disease that
leads to motor, sensory and cognitive deficits. MS symptoms are unpredictable and …

Multiple sclerosis (MS) is a chronic progressive, neurological disease characterized by the
targeted immune system-mediated destruction of central nervous system (CNS) myelin …

Multiple sclerosis (MS) is a chronic disease resulting from targeted destruction of central
nervous system (CNS) myelin. MS is suggested to be an autoimmune disease involving the …

Myelination by oligodendroglial cells (OLs) enables the propagation of action potentials
along neuronal axons, which is essential for rapid information flow in the central nervous …

MECP2 and its product methyl-CpG binding protein 2 (MeCP2) are associated with multiple
sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), which are …