▪ Abstract DNA secondary structure plays an important role in biology, genotyping
diagnostics, a variety of molecular biology techniques, in vitro–selected DNA catalysts …

Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

Polymerase chain reaction (PCR) is a basic molecular biology technique with a multiplicity
of uses, including deoxyribonucleic acid cloning and sequencing, functional analysis of …

The abbreviated name,'mfold web server', describes a number of closely related software
applications available on the World Wide Web (WWW) for the prediction of the secondary …

Background To understand an RNA sequence's mechanism of action, the structure must be
known. Furthermore, target RNA structure is an important consideration in the design of …

Transcription factors recognize specific genomic sequences to regulate complex gene-
expression programs. Although it is well-established that transcription factors bind to specific …

▪ Abstract DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects
mismatches generated during DNA replication and escape proofreading. MMR proteins also …

Oligonucleotides are designed to target RNA using base pairing rules, but they can be
hampered by poor cellular delivery and nonspecific stimulation of the immune system. Small …

In biology, nucleic acids are carriers of molecular information: DNA's base sequence stores
and imparts genetic instructions, while RNA's sequence plays the role of a messenger and a …

Spherical Nucleic Acids Page 1 We report a series of experiments and a theoretical model
designed to systematically define and evaluate contribut nanoparticle, e to the oligonucleotide …