Fluorination reactions of medicinal and biologically-active compounds will be discussed.
Late stage fluorination strategies of medicinal targets have recently attracted considerable …

Over the years, alkaloids derived from indole dearomatization, such as indolenine and
indolines have been evolved as promising therapeutic agents due to their important …

A metal-and initiator-free direct fluorination of arenes with the assistance of an amide group
is developed. This reaction proceeded under simple aqueous conditions with good …

Direct aminofluorination of alkenes enables the convenient synthesis of β‐fluorinated amine
compounds, which are important and valuable skeletons in medicinal chemistry. In recent …

We have discovered a ring-opening fluorination of bicyclic azaarenes. Upon treatment of
bicyclic azaarenes such as pyrazolo [1, 5-a] pyridines with electrophilic fluorinating agents …

A simple and practical protocol for the synthesis of 3-selanyl-benzo [b] furans mediated by
the SelectFluor® reagent was developed. This novel methodology provided a greener …

An enantioselective cascade Michael/hemiaminal formation of α, β-unsaturated
iminoindoles with aldehydes using a chiral aminomethylpyrrolidine catalyst bearing a …

A new and efficient method for the direct regioselective C2-amidation of various
functionalized indoles with several N-(2, 4, 6-trichlorobenzoyloxy) amides via Rh (III) …

A practical conversion of indoles into the corresponding 2‐oxindoles is achieved efficiently
using a hypervalent iodine reagent. This oxidation is amenable to different substituted …

Amination/Cyclization Cascade by Acid-Catalyzed Activation of Indolenine for the One-Pot
Synthesis of Phaitanthrin E | Organic Letters ACS ACS Publications C&EN CAS Find my …