Osteoarthritis (OA) is a multifactorial and increasingly prevalent degenerative disease that
affects the whole joint. The pathogenesis of OA is poorly understood and there is a lack of …

Osteoarthritis (OA) is a progressive and disabling musculoskeletal disease affecting millions
of people and resulting in major healthcare costs worldwide. It is the most common form of …

Osteoarthritis is a degenerative joint disease and a world-wide healthcare burden.
Characterized by cartilage degradation, subchondral bone thickening and osteophyte …

Rheumatoid arthritis (RA) is an autoimmune chronic inflammatory disease associated with
oxidative stress that causes excruciating pain, discomfort, and joint destruction. Ebselen …

Objective Osteoarthritis (OA) pathogenesis involves the interaction of articular cartilage with
surrounding tissues, which are innervated by tyrosine hydroxylase-positive (TH+) …

Osteoarthritis (OA) is a common aging-associated disease that clinically manifests as joint
pain, mobility limitations, and compromised quality of life. Today, OA treatment is limited to …

Background Oxidative stress plays an important role in the pathogenesis of disease, and the
antioxidant physiological effect of omega-3 from fish oil may lead to improvement of canine …

Nrf2 is a master transcriptional regulator of a number of genes involved in the adaptive
response to oxidative stress. Among the genes upregulated by Nrf2, heme oxygenase-1 (HO …

Objective Osteoarthritis (OA) is one of the leading causes of disability within the adult
population. Currently, its diagnosis is mainly based on clinical examination and standard …

The purpose of this study is to investigate the antioxidant and anti-inflammatory properties of
silicon (Si) in the RAW 264.7 murine macrophage cell line. Lipopolysaccharide (LPS) was …