Moxifloxacin (Avelox®) is a fluoroquinolone antibacterial with a methoxy group in the C-8
position and a bulky C-7 side chain. Moxifloxacin is approved for use in the treatment of …

This synopsis of published literature summarises data on the in vitro antibacterial activity
and pharmacodynamics of fluoroquinolones. Data were compiled for ciprofloxacin …

Posterior capsule opacification (PCO) still remains the most frequent long term complication
after cataract surgery, while endophthalmitis is rare but severe and should be prevented at …

Background. Oral combination therapy with fluoroquinolones plus rifampicin is a promising
alternative to standard parenteral therapy for staphylococcal infections. Methods. In a …

Background The role of oral antibiotic therapy in treating infective endocarditis (IE) is not
well established. Methods We searched MEDLINE, EMBASE and Scopus for studies in …

The purpose of this study was to quantitatively compare, in a rabbit keratitis model, the levels
of effectiveness of moxifloxacin, levofloxacin, and ciprofloxacin for the treatment of …

The efficacy of antibiotic monotherapy and combination therapy in the treatment of implant-
associated infection by Staphylococcus aureus was evaluated in an animal study. The …

Cataract is highly prevalent among old population worldwide and replacement of the
opacified crystalline lens by an intraocular lens (IOL) is the safest and the most effective …

Ertapenem, a parenteral broad-spectrum 1-β-methyl-carbapenem, was licensed 5 years ago
for clinical practice in the US and Europe. The substance has a good in vitro activity against …

ABSTRACT A two-compartment in vitro pharmacokinetic-pharmacodynamic model, with full
computer-controlled devices, was used to accurately simulate human plasma …