Retinitis pigmentosa (RP) encompasses a group of inherited retinal dystrophies
characterized by the primary degeneration of rod and cone photoreceptors. RP is a leading …

Vitamin A is an essential fat-soluble vitamin that occurs in various chemical forms. It is
essential for several physiological processes. Either hyper-or hypovitaminosis can be …

The tear film is a layer of body fluid that maintains the homeostasis of the ocular surface. The
superior accessibility of tears and the presence of a high concentration of functional proteins …

Purpose: To study if human embryonic stem cell–derived photoreceptors could survive and
function without the support of retinal pigment epithelium (RPE) after transplantation into …

Over 2 million people worldwide are suffering from gene-related retinal diseases, inherited
or acquired, and over 270 genes have been identified which are found to be responsible for …

This review explores the usefulness retinoic acid (RA) related physiological factors as
possible biomarkers of embryotoxicity. RA is involved in the morphogenesis of the early …

The retinoid nuclear receptor pathway, activated by the vitamin A metabolite retinoic acid,
has been extensively investigated for over a century. This study has resulted in conflicting …

Vitamin A is an essential nutrient necessary for numerous basic physiological functions,
including reproduction and development, immune cell differentiation and communication, as …

Polybrominated diphenyl ethers (PBDEs) are a class of widely used flame retardants, and
their residue in the environment may threaten the ecosystem and human health. The …

Background Stroke is the second leading cause of death worldwide, and observational
studies have suggested a correlation between antioxidants and reduced stroke risk …